Keratinocyte-specific deletion of SHARPIN induces atopic dermatitis-like inflammation in mice

Spontaneous mutations in the SHANK-associated RH domain interacting protein (Sharpin) resulted in a severe autoinflammatory type of chronic proliferative dermatitis, inflammation in other organs, and lymphoid organ defects. To determine whether cell-type restricted loss of Sharpin causes similar les...

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Detalles Bibliográficos
Autores principales: Sundberg, John P., Pratt, C. Herbert, Goodwin, Leslie P., Silva, Kathleen A., Kennedy, Victoria E., Potter, Christopher S., Dunham, Anisa, Sundberg, Beth A., HogenEsch, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371178/
https://www.ncbi.nlm.nih.gov/pubmed/32687504
http://dx.doi.org/10.1371/journal.pone.0235295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371178/
https://www.ncbi.nlm.nih.gov/pubmed/32687504
http://dx.doi.org/10.1371/journal.pone.0235295

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