Cargando…

IL18 signaling promotes homing of mature Tregs into the thymus

Foxp3+ regulatory T cells (Tregs) are potent suppressor cells, essential for the maintenance of immune homeostasis. Most Tregs develop in the thymus and are then released into the immune periphery. However, some Tregs populate the thymus and constitute a major subset of yet poorly understood cells....

Descripción completa

Detalles Bibliográficos
Autores principales:	Peligero-Cruz, Cristina, Givony, Tal, Sebé-Pedrós, Arnau, Dobeš, Jan, Kadouri, Noam, Nevo, Shir, Roncato, Francesco, Alon, Ronen, Goldfarb, Yael, Abramson, Jakub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371425/ https://www.ncbi.nlm.nih.gov/pubmed/32687059 http://dx.doi.org/10.7554/eLife.58213

Ejemplares similares

Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation
por: Goldfarb, Yael, et al.
Publicado: (2021)

Ageing compromises mouse thymus function and remodels epithelial cell differentiation
por: Baran-Gale, Jeanette, et al.
Publicado: (2020)

Pauci-symptomatic disseminated tuberculosis revealed by an increase in the specific antigen of the prostate
por: Kadouri, Youssef, et al.
Publicado: (2020)

CCR7 defines a precursor for murine iNKT cells in thymus and periphery
por: Wang, Haiguang, et al.
Publicado: (2018)

Somatic hypermutation of T cell receptor α chain contributes to selection in nurse shark thymus
por: Ott, Jeannine A, et al.
Publicado: (2018)

Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo
por: Fernandes, Ricardo A, et al.
Publicado: (2020)

Imbalance of Th22/Treg cells causes microinflammation in uremic patients undergoing hemodialysis
por: Ren, Tingting, et al.
Publicado: (2019)

ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation
por: Tian, Miaomiao, et al.
Publicado: (2021)

Orthology Clusters from Gene Trees with Possvm
por: Grau-Bové, Xavier, et al.
Publicado: (2021)

The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity
por: de Mendoza, Alex, et al.
Publicado: (2014)

A Genomic Survey of HECT Ubiquitin Ligases in Eukaryotes Reveals Independent Expansions of the HECT System in Several Lineages
por: Grau-Bové, Xavier, et al.
Publicado: (2013)

The Eukaryotic Ancestor Had a Complex Ubiquitin Signaling System of Archaeal Origin
por: Grau-Bové, Xavier, et al.
Publicado: (2015)

Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity
por: Zhang, Xue-Song, et al.
Publicado: (2018)

Capacity of tTreg generation is not impaired in the atrophied thymus
por: Oh, Jiyoung, et al.
Publicado: (2017)

Quantitative modeling of the effect of antigen dosage on B-cell affinity distributions in maturating germinal centers
por: Molari, Marco, et al.
Publicado: (2020)

The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function
por: Li, Shasha, et al.
Publicado: (2022)

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR(+)NKG2A(-) NK cells
por: Bennstein, Sabrina Bianca, et al.
Publicado: (2020)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

Demonstrative Imaging of Emphysematous Cystitis
por: May, Tal, et al.
Publicado: (2016)

Evolution and Classification of Myosins, a Paneukaryotic Whole-Genome Approach
por: Sebé-Pedrós, Arnau, et al.
Publicado: (2014)

Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors
por: Cohen, Hadar, et al.
Publicado: (2022)

MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions
por: Baran, Yael, et al.
Publicado: (2019)

Role of autoantibodies and blood–brain barrier leakage in cognitive impairment in systemic lupus erythematosus
por: Hanly, John G, et al.
Publicado: (2022)

IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25(+)Foxp3(-) T cells
por: Tomala, Jakub, et al.
Publicado: (2021)

Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling
por: Sun, Kai, et al.
Publicado: (2022)

Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells
por: Roncato, Francesco, et al.
Publicado: (2021)

A Broad Genomic Survey Reveals Multiple Origins and Frequent Losses in the Evolution of Respiratory Hemerythrins and Hemocyanins
por: Martín-Durán, José M., et al.
Publicado: (2013)

Antibodies to repeat-containing antigens in Plasmodium falciparum are exposure-dependent and short-lived in children in natural malaria infections
por: Raghavan, Madhura, et al.
Publicado: (2023)

Differences in the inflammatory proteome of East African and Western European adults and associations with environmental and dietary factors
por: Temba, Godfrey S, et al.
Publicado: (2023)

Paediatric autoimmune encephalopathies: clinical features, laboratory investigations and outcomes in patients with or without antibodies to known central nervous system autoantigens
por: Hacohen, Yael, et al.
Publicado: (2013)

A single-cell view on alga-virus interactions reveals sequential transcriptional programs and infection states
por: Ku, Chuan, et al.
Publicado: (2020)

Appearance and Maturation of T-Cell Subsets During Rat Thymus Ontogeny
por: Vicente, A., et al.
Publicado: (1998)

DUAL REGULATORY ROLE OF THE THYMUS IN THE MATURATION OF IMMUNE RESPONSE IN THE RABBIT
por: Taniguchi, Masaru, et al.
Publicado: (1974)

Cannot write session to /tmp/vufind_sessions/sess_qqg1p1rrd7o959bbmj9iamikgk