Nanosized Cubosomal Thermogelling Dispersion Loaded with Saquinavir Mesylate to Improve Its Bioavailability: Preparation, Optimization, in vitro and in vivo Evaluation

BACKGROUND: Low bioavailability and poor permeability of the blood–brain barrier are problematic when delivering therapeutic agents and particularly anti–human immunodeficiency virus therapy to the central nervous system. The intranasal route offers an alternative for central nervous system delivery...

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Detalles Bibliográficos
Autor principal: Hosny, Khaled M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371439/
https://www.ncbi.nlm.nih.gov/pubmed/32764940
http://dx.doi.org/10.2147/IJN.S261855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371439/
https://www.ncbi.nlm.nih.gov/pubmed/32764940
http://dx.doi.org/10.2147/IJN.S261855

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