Cargando…

Modulation of MnSOD and FoxM1 Is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells

BACKGROUND: Manganese superoxide dismutase (MnSOD) induces FoxM1 expression, subsequently contributing to migration in several cancer cells. Isovitexin (ISOV) was recently found to downregulate MnSOD and FoxM1, decreasing stemness in hepatocellular carcinoma (HCC) stem-like cells (HCSLCs). The curre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Yebei, Cao, Xiaocheng, Liu, Lihua, Cao, Xiaozheng, Yuan, Qing, Li, Xiang, Cui, Yinghong, Xu, Chang, Zou, Chang, Ren, Kaiqun, Cao, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371559/ https://www.ncbi.nlm.nih.gov/pubmed/32765079 http://dx.doi.org/10.2147/CMAR.S245283

Ejemplares similares

Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1
por: Cao, Xiaocheng, et al.
Publicado: (2019)

Retraction Note: Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1
por: Cao, Xiaocheng, et al.
Publicado: (2022)

Genistein inhibits lung cancer cell stem-like characteristics by modulating MnSOD and FoxM1 expression
por: Fu, Zhimin, et al.
Publicado: (2020)

Modulation of MnSOD and FoxM1 is Involved in Invasion and EMT Suppression by Isovitexin in Hepatocellular Carcinoma Cells [Retraction]
Publicado: (2022)

Isovitexin Suppresses Stemness of Lung Cancer Stem-Like Cells through Blockage of MnSOD/CaMKII/AMPK Signaling and Glycolysis Inhibition
por: Liu, Fei, et al.
Publicado: (2021)

The DNMT1/miR-34a/FOXM1 Axis Contributes to Stemness of Liver Cancer Cells
por: Cao, Xiaocheng, et al.
Publicado: (2020)

Upregulation of FoxM1 by MnSOD Overexpression Contributes to Cancer Stem-Like Cell Characteristics in the Lung Cancer H460 Cell Line
por: Fu, Zhimin, et al.
Publicado: (2018)

Tetramerization Reinforces the Dimer Interface of MnSOD
por: Sheng, Yuewei, et al.
Publicado: (2013)

Associations between the phenotype and genotype of MnSOD and catalase in periodontal disease
por: Lee, Chang-Yu, et al.
Publicado: (2019)

Modeling and phylogeny analysis of bread wheat MnSOD
por: Sheoran, Sonia, et al.
Publicado: (2011)

Modulation of MnSOD in Cancer:Epidemiological and Experimental Evidence
por: Kim, Aekyong
Publicado: (2010)

The Functional Role of MnSOD as a Biomarker of Human Diseases and Therapeutic Potential of a New Isoform of a Human Recombinant MnSOD
por: Borrelli, Antonella, et al.
Publicado: (2014)

Association between MnSOD Activity and Cognitive Impairment in Unmedicated First-Episode Schizophrenia: Regulated by MnSOD Ala-9Val Gene Polymorphism
por: Wang, Dong Mei, et al.
Publicado: (2022)

Association of MnSOD AA Genotype with the Progression of Prostate Cancer
por: Iguchi, Taro, et al.
Publicado: (2015)

The structure–function relationships and physiological roles of MnSOD mutants
por: Bonetta Valentino, Rosalin
Publicado: (2022)

MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management
por: Bellot, Gregory Lucien, et al.
Publicado: (2018)

Preferential selection of MnSOD transcripts in proliferating normal and cancer cells
por: Chaudhuri, Leena, et al.
Publicado: (2011)

Aging, MnSOD, and hormesis mechanisms converge on liver mUPR
por: Shen, Jie, et al.
Publicado: (2013)

Reduction in MnSOD promotes the migration and invasion of squamous carcinoma cells
por: Fan, Jhen-Jia, et al.
Publicado: (2019)

HADC regulates the diabetic vascular endothelial dysfunction by targetting MnSOD
por: Hou, Qian, et al.
Publicado: (2018)

The level of MnSOD is directly correlated with grade of brain tumours of neuroepithelial origin.
por: Landriscina, M., et al.
Publicado: (1996)

MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes
por: Deruy, Emeric, et al.
Publicado: (2010)

Roles of the Two-MnSOD System of Stenotrophomonas maltophilia in the Alleviation of Superoxide Stress
por: Jair, Herng-Woei, et al.
Publicado: (2019)

Transcriptomic characterization of the enzymatic antioxidants FeSOD, MnSOD, APX and KatG in the dinoflagellate genus Symbiodinium
por: Krueger, Thomas, et al.
Publicado: (2015)

Oxidative Stress Induced by MnSOD-p53 Interaction: Pro- or Anti-Tumorigenic?
por: Robbins, Delira, et al.
Publicado: (2012)

MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity
por: Souiden, Yosra, et al.
Publicado: (2016)

Immunohistochemical assessment of mitochondrial superoxide dismutase (MnSOD) in colorectal premalignant and malignant lesions
por: Piecuch, Adam, et al.
Publicado: (2016)

MnSOD mediated by HSV vectors in the periaqueductal gray suppresses morphine withdrawal in rats
por: Iida, Takafumi, et al.
Publicado: (2017)

No Association of Four Candidate Genetic Variants in MnSOD and SYNIII with Parkinson's Disease in Two Chinese Populations
por: Yu, Wen Juan, et al.
Publicado: (2014)

Association between Polymorphisms of Antioxidant Gene (MnSOD, CAT, and GPx1) and Risk of Coronary Artery Disease
por: Yeh, Hseng-Long, et al.
Publicado: (2018)

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress
por: Ozden, Ozkan, et al.
Publicado: (2011)

Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of Human
por: Venkatachalam, Gireedhar, et al.
Publicado: (2009)

Characterization of the aodA, dnmA, mnSOD and pimA genes in Aspergillus nidulans
por: Leiter, Éva, et al.
Publicado: (2016)

Barley beta-glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment
por: Agostini, Silvia, et al.
Publicado: (2015)

Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas
por: Vidimar, Vania, et al.
Publicado: (2016)

Significance of AtMTM1 and AtMTM2 for Mitochondrial MnSOD Activation in Arabidopsis
por: Hu, Shu-Hsuan, et al.
Publicado: (2021)

Small-Molecule Mn Antioxidants in Caenorhabditis elegans and Deinococcus radiodurans Supplant MnSOD Enzymes during Aging and Irradiation
por: Gaidamakova, Elena K., et al.
Publicado: (2022)

Impacts of Mn, Fe, and Oxidative Stressors on MnSOD Activation by AtMTM1 and AtMTM2 in Arabidopsis
por: Hu, Shu-Hsuan, et al.
Publicado: (2022)

Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis
por: Liang, Xiao, et al.
Publicado: (2019)

Peroxynitrite induced mitochondrial biogenesis following MnSOD knockdown in normal rat kidney (NRK) cells()
por: Marine, Akira, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hh2k3nuq39fbec8q9719v8mckj