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Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells

BACKGROUND: Metformin may exert the anticancer effect on multiple types of cancers and some potential mechanisms have been suggested. Our study was designed to determine the effect of metformin on the cell autophagy and autophagic flux via the AMPK-mTOR signaling pathway in human hepatocellular carc...

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Detalles Bibliográficos
Autores principales: Gao, Chun, Fang, Long, Zhang, Hui, Zhang, Wei-Shuo, Li, Xiao-Ou, Du, Shi-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371564/
https://www.ncbi.nlm.nih.gov/pubmed/32765083
http://dx.doi.org/10.2147/CMAR.S257966