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FKS1 mutation associated with decreased echinocandin susceptibility of Aspergillus fumigatus following anidulafungin exposure
Invasive aspergillosis (IA) is a potentially lethal infection that affects mostly immunocompromised patients caused by Aspergillus fumigatus. Echinocandins are a second-line therapy against IA, used as a salvage therapy as well as for empirical or prophylactic therapy. Although they cause lysis of g...
Autores principales: | e Silva, Ana Pinto, Miranda, Isabel Marcos, Branco, Joana, Oliveira, Patricia, Faria-Ramos, Isabel, Silva, Raquel M., Rodrigues, Acácio Gonçalves, Costa-de-Oliveira, Sofia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371691/ https://www.ncbi.nlm.nih.gov/pubmed/32686741 http://dx.doi.org/10.1038/s41598-020-68706-8 |
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