Human essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses

Polygenic risk scores (PRSs) for essential hypertension, calculated from > 900 genomic loci, were recently found to explain a significant fraction of hypertension heritability and complications. To investigate whether variation of hypertension PRS also captures variation of antihypertensive drug...

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Detalles Bibliográficos
Autores principales: Sánez Tähtisalo, Heini, Ruotsalainen, Sanni, Mars, Nina, Porthan, Kimmo, Oikarinen, Lasse, Virolainen, Juha, Fyhrquist, Frej, Ripatti, Samuli, Kontula, Kimmo K., Hiltunen, Timo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371738/
https://www.ncbi.nlm.nih.gov/pubmed/32686723
http://dx.doi.org/10.1038/s41598-020-68878-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371738/
https://www.ncbi.nlm.nih.gov/pubmed/32686723
http://dx.doi.org/10.1038/s41598-020-68878-3

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