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Fas mutation reduces obesity by increasing IL-4 and IL-10 expression and promoting white adipose tissue browning

Brown adipose tissue generates heat via the mitochondrial uncoupling protein UCP1 to protect against obesity and hypothermia. Fas mutant MRL/lpr mice exhibit a significantly leaner phenotype compared to wild type MRL/MpJ mice. In this study, we evaluated the inflammatory cell population in the adipo...

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Detalles Bibliográficos
Autores principales:	Choi, Eun Wha, Lee, Minjae, Song, Ji Woo, Kim, Kyeongdae, Lee, Jungmin, Yang, Jehoon, Lee, Seo Hyun, Kim, Il Yong, Choi, Jae-Hoon, Seong, Je Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371740/ https://www.ncbi.nlm.nih.gov/pubmed/32686763 http://dx.doi.org/10.1038/s41598-020-68971-7

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