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ZAK Inhibitor PLX4720 Promotes Extrusion of Transformed Cells via Cell Competition

Previous studies have revealed that, at the initial step of carcinogenesis, transformed cells are often eliminated from epithelia via cell competition with the surrounding normal cells. In this study, we performed cell competition-based high-throughput screening for chemical compounds using cultured...

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Detalles Bibliográficos
Autores principales: Maruyama, Takeshi, Sasaki, Ayana, Iijima, Sayuri, Ayukawa, Shiyu, Goda, Nobuhito, Tazuru, Keisuke, Hashimoto, Norikazu, Hayashi, Takashi, Kozawa, Kei, Sato, Nanami, Ishikawa, Susumu, Morita, Tomoko, Fujita, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371749/
https://www.ncbi.nlm.nih.gov/pubmed/32688284
http://dx.doi.org/10.1016/j.isci.2020.101327