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Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s
BACKGROUND: The prevalence of allergic rhinitis (AR), an environment- and lifestyle-dependent condition, has been constantly increasing in Korea. Although the environment and lifestyle of the Korean people have recently undergone rapid changes, corresponding changes in the characteristics of AR pati...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371806/ https://www.ncbi.nlm.nih.gov/pubmed/32834824 http://dx.doi.org/10.1186/s13223-020-00455-9 |
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author | Kim, Ji Heui Kim, Shin Ae Ku, Ja Yoon Cho, Won Ki Shin, Chol Ho |
author_facet | Kim, Ji Heui Kim, Shin Ae Ku, Ja Yoon Cho, Won Ki Shin, Chol Ho |
author_sort | Kim, Ji Heui |
collection | PubMed |
description | BACKGROUND: The prevalence of allergic rhinitis (AR), an environment- and lifestyle-dependent condition, has been constantly increasing in Korea. Although the environment and lifestyle of the Korean people have recently undergone rapid changes, corresponding changes in the characteristics of AR patients have not been well documented. Therefore, we aimed to outline the changes in allergens and clinical manifestations of AR in Korean patients from the 1990s and 2010s. METHODS: We reviewed 1447 and 3388 AR patients who visited the same tertiary hospital in the 1990s and 2010s, respectively. All patients were diagnosed with AR based on the presence of characteristic symptoms, positive skin prick test results, and answered a symptom questionnaire at the time of visit. We compared differences in the allergens and results of the symptom questionnaire between the two sets of patients. RESULTS: When compared with the 1990s, the rate of sensitization to house dust mites, cockroaches, Aspergillus, Alternaria, and tree pollen significantly increased and that to cat fur significantly decreased in patients from the 2010s (all P < 0.05). Male predominance was observed with two peaks in the age distribution of patients from the 2010s. The proportion of patients with moderate-to-severe nasal obstruction and itching of the nose/eye increased (each P < 0.05) and that of patients with minor symptoms such as olfactory disturbances, cough, sore throat, and fatigue also increased (all P < 0.01) in the 2010s. CONCLUSIONS: Allergen reactivity and type and symptom severity in Korean AR patients significantly varied between the 1990s and 2010s. Our results may therefore be helpful for patient counseling and management. |
format | Online Article Text |
id | pubmed-7371806 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73718062020-07-21 Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s Kim, Ji Heui Kim, Shin Ae Ku, Ja Yoon Cho, Won Ki Shin, Chol Ho Allergy Asthma Clin Immunol Research BACKGROUND: The prevalence of allergic rhinitis (AR), an environment- and lifestyle-dependent condition, has been constantly increasing in Korea. Although the environment and lifestyle of the Korean people have recently undergone rapid changes, corresponding changes in the characteristics of AR patients have not been well documented. Therefore, we aimed to outline the changes in allergens and clinical manifestations of AR in Korean patients from the 1990s and 2010s. METHODS: We reviewed 1447 and 3388 AR patients who visited the same tertiary hospital in the 1990s and 2010s, respectively. All patients were diagnosed with AR based on the presence of characteristic symptoms, positive skin prick test results, and answered a symptom questionnaire at the time of visit. We compared differences in the allergens and results of the symptom questionnaire between the two sets of patients. RESULTS: When compared with the 1990s, the rate of sensitization to house dust mites, cockroaches, Aspergillus, Alternaria, and tree pollen significantly increased and that to cat fur significantly decreased in patients from the 2010s (all P < 0.05). Male predominance was observed with two peaks in the age distribution of patients from the 2010s. The proportion of patients with moderate-to-severe nasal obstruction and itching of the nose/eye increased (each P < 0.05) and that of patients with minor symptoms such as olfactory disturbances, cough, sore throat, and fatigue also increased (all P < 0.01) in the 2010s. CONCLUSIONS: Allergen reactivity and type and symptom severity in Korean AR patients significantly varied between the 1990s and 2010s. Our results may therefore be helpful for patient counseling and management. BioMed Central 2020-07-01 /pmc/articles/PMC7371806/ /pubmed/32834824 http://dx.doi.org/10.1186/s13223-020-00455-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Kim, Ji Heui Kim, Shin Ae Ku, Ja Yoon Cho, Won Ki Shin, Chol Ho Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
title | Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
title_full | Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
title_fullStr | Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
title_full_unstemmed | Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
title_short | Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
title_sort | comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371806/ https://www.ncbi.nlm.nih.gov/pubmed/32834824 http://dx.doi.org/10.1186/s13223-020-00455-9 |
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