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Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions
Studies on action observation mostly described the activation of a network of cortical areas, while less investigation focused specifically on the activation and role of subcortical nodes. In the present fMRI study, we investigated the recruitment of cerebellum and basal ganglia during the execution...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371896/ https://www.ncbi.nlm.nih.gov/pubmed/32686738 http://dx.doi.org/10.1038/s41598-020-68928-w |
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author | Errante, Antonino Fogassi, Leonardo |
author_facet | Errante, Antonino Fogassi, Leonardo |
author_sort | Errante, Antonino |
collection | PubMed |
description | Studies on action observation mostly described the activation of a network of cortical areas, while less investigation focused specifically on the activation and role of subcortical nodes. In the present fMRI study, we investigated the recruitment of cerebellum and basal ganglia during the execution and observation of object manipulation performed with the right hand. The observation conditions consisted in: (a) observation of manipulative actions; (b) observation of sequences of random finger movements. In the execution conditions, participants had to perform the same actions or movements as in (a) and (b), respectively. The results of conjunction analysis showed significant shared activations during both observation and execution of manipulation in several subcortical structures, including: (1) cerebellar lobules V, VI, crus I, VIIIa and VIIIb (bilaterally); (2) globus pallidus, bilaterally, and left subthalamic nucleus; (3) red nucleus (bilaterally) and left thalamus. These findings support the hypothesis that the action observation/execution network also involves subcortical structures, such as cerebellum and basal ganglia, forming an integrated network. This suggests possible mechanisms, involving these subcortical structures, underlying learning of new motor skills, through action observation and imitation. |
format | Online Article Text |
id | pubmed-7371896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-73718962020-07-22 Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions Errante, Antonino Fogassi, Leonardo Sci Rep Article Studies on action observation mostly described the activation of a network of cortical areas, while less investigation focused specifically on the activation and role of subcortical nodes. In the present fMRI study, we investigated the recruitment of cerebellum and basal ganglia during the execution and observation of object manipulation performed with the right hand. The observation conditions consisted in: (a) observation of manipulative actions; (b) observation of sequences of random finger movements. In the execution conditions, participants had to perform the same actions or movements as in (a) and (b), respectively. The results of conjunction analysis showed significant shared activations during both observation and execution of manipulation in several subcortical structures, including: (1) cerebellar lobules V, VI, crus I, VIIIa and VIIIb (bilaterally); (2) globus pallidus, bilaterally, and left subthalamic nucleus; (3) red nucleus (bilaterally) and left thalamus. These findings support the hypothesis that the action observation/execution network also involves subcortical structures, such as cerebellum and basal ganglia, forming an integrated network. This suggests possible mechanisms, involving these subcortical structures, underlying learning of new motor skills, through action observation and imitation. Nature Publishing Group UK 2020-07-20 /pmc/articles/PMC7371896/ /pubmed/32686738 http://dx.doi.org/10.1038/s41598-020-68928-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Errante, Antonino Fogassi, Leonardo Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
title | Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
title_full | Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
title_fullStr | Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
title_full_unstemmed | Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
title_short | Activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
title_sort | activation of cerebellum and basal ganglia during the observation and execution of manipulative actions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371896/ https://www.ncbi.nlm.nih.gov/pubmed/32686738 http://dx.doi.org/10.1038/s41598-020-68928-w |
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