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Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens

Langerhans cells (LCs) are antigen-presenting cells that reside in the skin. They uniquely express high levels of the C-type lectin receptor Langerin (CD207), which is an attractive target for antigen delivery in immunotherapeutic vaccination strategies against cancer. We here assess a library of 20...

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Detalles Bibliográficos
Autores principales: Li, Rui-Jun Eveline, Hogervorst, Tim P., Achilli, Silvia, Bruijns, Sven C. M., Spiekstra, Sander, Vivès, Corinne, Thépaut, Michel, Filippov, Dmitri V., van der Marel, Gijs A., van Vliet, Sandra J., Fieschi, Franck, Codée, Jeroen D. C., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371993/
https://www.ncbi.nlm.nih.gov/pubmed/32760719
http://dx.doi.org/10.3389/fcell.2020.00556