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Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia
Introduction: Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372105/ https://www.ncbi.nlm.nih.gov/pubmed/32760691 http://dx.doi.org/10.3389/fpubh.2020.00381 |
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author | Harapan, Harapan Wagner, Abram L. Yufika, Amanda Winardi, Wira Anwar, Samsul Gan, Alex Kurniawan Setiawan, Abdul Malik Rajamoorthy, Yogambigai Sofyan, Hizir Mudatsir, Mudatsir |
author_facet | Harapan, Harapan Wagner, Abram L. Yufika, Amanda Winardi, Wira Anwar, Samsul Gan, Alex Kurniawan Setiawan, Abdul Malik Rajamoorthy, Yogambigai Sofyan, Hizir Mudatsir, Mudatsir |
author_sort | Harapan, Harapan |
collection | PubMed |
description | Introduction: Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population in Indonesia. Methods: A cross-sectional online survey was conducted between March 25 and April 6, 2020. Participants were asked if they would accept a free vaccine which was 95 or 50% effective. Using a logistic regression model, we assessed the associations between sociodemographic characteristics, exposure to COVID-19 information, or perceived risk of infection with acceptance of a hypothetical COVID-19 vaccine. Results: Among 1,359 respondents, 93.3% of respondents (1,268/1,359) would like to be vaccinated for a 95% effective vaccine, but this acceptance decreased to 67.0% (911/1,359) for a vaccine with 50% effectiveness. For a 95% effective vaccine, being a healthcare worker and having a higher perceived risk of COVID-19 infection were associated with higher acceptance, adjusted odds ratio (aOR): 2.01; 95%CI: 1.01, 4.00 and aOR: 2.21; 95%CI: 1.07, 4.59, respectively; compared to civil servants, being retired was associated with less acceptance (aOR: 0.15; 95%CI: 0.04, 0.63). For a 50% effective vaccine, being a healthcare worker was also associated with greater acceptance, aOR: 1.57; 95%CI: 1.12, 2.20. Conclusion: Acceptance of a COVID-19 vaccine was highly influenced by the baseline effectiveness of the vaccine. Preparing the general population to accept a vaccine with relatively low effectiveness may be difficult. |
format | Online Article Text |
id | pubmed-7372105 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73721052020-08-04 Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia Harapan, Harapan Wagner, Abram L. Yufika, Amanda Winardi, Wira Anwar, Samsul Gan, Alex Kurniawan Setiawan, Abdul Malik Rajamoorthy, Yogambigai Sofyan, Hizir Mudatsir, Mudatsir Front Public Health Public Health Introduction: Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population in Indonesia. Methods: A cross-sectional online survey was conducted between March 25 and April 6, 2020. Participants were asked if they would accept a free vaccine which was 95 or 50% effective. Using a logistic regression model, we assessed the associations between sociodemographic characteristics, exposure to COVID-19 information, or perceived risk of infection with acceptance of a hypothetical COVID-19 vaccine. Results: Among 1,359 respondents, 93.3% of respondents (1,268/1,359) would like to be vaccinated for a 95% effective vaccine, but this acceptance decreased to 67.0% (911/1,359) for a vaccine with 50% effectiveness. For a 95% effective vaccine, being a healthcare worker and having a higher perceived risk of COVID-19 infection were associated with higher acceptance, adjusted odds ratio (aOR): 2.01; 95%CI: 1.01, 4.00 and aOR: 2.21; 95%CI: 1.07, 4.59, respectively; compared to civil servants, being retired was associated with less acceptance (aOR: 0.15; 95%CI: 0.04, 0.63). For a 50% effective vaccine, being a healthcare worker was also associated with greater acceptance, aOR: 1.57; 95%CI: 1.12, 2.20. Conclusion: Acceptance of a COVID-19 vaccine was highly influenced by the baseline effectiveness of the vaccine. Preparing the general population to accept a vaccine with relatively low effectiveness may be difficult. Frontiers Media S.A. 2020-07-14 /pmc/articles/PMC7372105/ /pubmed/32760691 http://dx.doi.org/10.3389/fpubh.2020.00381 Text en Copyright © 2020 Harapan, Wagner, Yufika, Winardi, Anwar, Gan, Setiawan, Rajamoorthy, Sofyan and Mudatsir. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Harapan, Harapan Wagner, Abram L. Yufika, Amanda Winardi, Wira Anwar, Samsul Gan, Alex Kurniawan Setiawan, Abdul Malik Rajamoorthy, Yogambigai Sofyan, Hizir Mudatsir, Mudatsir Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia |
title | Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia |
title_full | Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia |
title_fullStr | Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia |
title_full_unstemmed | Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia |
title_short | Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia |
title_sort | acceptance of a covid-19 vaccine in southeast asia: a cross-sectional study in indonesia |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372105/ https://www.ncbi.nlm.nih.gov/pubmed/32760691 http://dx.doi.org/10.3389/fpubh.2020.00381 |
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