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Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress

Alzheimer’s disease (AD) has become a major disease contributing to human death and is thought to be closely related to the aging process. The rich antioxidant substances in plants have been shown to play a role in delaying aging, and in recent years, significant research has focused on also examini...

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Detalles Bibliográficos
Autores principales: Cui, Xiaoji, Lin, Qinlu, Liang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372124/
https://www.ncbi.nlm.nih.gov/pubmed/32760268
http://dx.doi.org/10.3389/fnagi.2020.00209
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author Cui, Xiaoji
Lin, Qinlu
Liang, Ying
author_facet Cui, Xiaoji
Lin, Qinlu
Liang, Ying
author_sort Cui, Xiaoji
collection PubMed
description Alzheimer’s disease (AD) has become a major disease contributing to human death and is thought to be closely related to the aging process. The rich antioxidant substances in plants have been shown to play a role in delaying aging, and in recent years, significant research has focused on also examining their potential role in AD onset and progression. Many plant-derived antioxidant research studies have provided insights for the future treatment and prevention of AD. This article reviews various types of plant-derived antioxidants with anti-aging effects on neurons. Also it distinguishes the different types of active substances that exhibit different degrees of protection for the nervous system and summarizes the mechanism thereof. Plant-derived antioxidants with neuroprotective functions can protect various components of the nervous system in a variety of ways and can have a positive impact on interventions to prevent and alleviate AD. Furthermore, when considering neuroprotective agents, glial cells also contribute to the defense of the nervous system and should not be ignored.
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spelling pubmed-73721242020-08-04 Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress Cui, Xiaoji Lin, Qinlu Liang, Ying Front Aging Neurosci Neuroscience Alzheimer’s disease (AD) has become a major disease contributing to human death and is thought to be closely related to the aging process. The rich antioxidant substances in plants have been shown to play a role in delaying aging, and in recent years, significant research has focused on also examining their potential role in AD onset and progression. Many plant-derived antioxidant research studies have provided insights for the future treatment and prevention of AD. This article reviews various types of plant-derived antioxidants with anti-aging effects on neurons. Also it distinguishes the different types of active substances that exhibit different degrees of protection for the nervous system and summarizes the mechanism thereof. Plant-derived antioxidants with neuroprotective functions can protect various components of the nervous system in a variety of ways and can have a positive impact on interventions to prevent and alleviate AD. Furthermore, when considering neuroprotective agents, glial cells also contribute to the defense of the nervous system and should not be ignored. Frontiers Media S.A. 2020-07-14 /pmc/articles/PMC7372124/ /pubmed/32760268 http://dx.doi.org/10.3389/fnagi.2020.00209 Text en Copyright © 2020 Cui, Lin and Liang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Cui, Xiaoji
Lin, Qinlu
Liang, Ying
Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress
title Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress
title_full Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress
title_fullStr Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress
title_full_unstemmed Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress
title_short Plant-Derived Antioxidants Protect the Nervous System From Aging by Inhibiting Oxidative Stress
title_sort plant-derived antioxidants protect the nervous system from aging by inhibiting oxidative stress
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372124/
https://www.ncbi.nlm.nih.gov/pubmed/32760268
http://dx.doi.org/10.3389/fnagi.2020.00209
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