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NR4A1 Methylation Associated Multimodal Neuroimaging Patterns Impaired in Temporal Lobe Epilepsy
DNA hypermethylation has been widely observed in temporal lobe epilepsy (TLE), in which NR4A1 knockdown has been reported to be able to alleviate seizure severity in mouse model, while the underlying methylation-imaging pathway modulated by aberrant methylation levels of NR4A1 remains to be clarifie...
Autores principales: | Zhi, Dongmei, Wu, Wenyue, Xiao, Bo, Qi, Shile, Jiang, Rongtao, Yang, Xingdong, Yang, Jian, Xiao, Wenbiao, Liu, Chaorong, Long, Hongyu, Calhoun, Vince D., Long, Lili, Sui, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372187/ https://www.ncbi.nlm.nih.gov/pubmed/32760244 http://dx.doi.org/10.3389/fnins.2020.00727 |
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