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Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review
Asthma patients have commonly been prescribed inhaled corticosteroids (ICSs) as the first line of control therapy. ICSs are associated with an increased risk of pneumonia in chronic obstructive airway disease (COPD) patients. However, the evidence remains controversial in asthma patients. Several ob...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372200/ https://www.ncbi.nlm.nih.gov/pubmed/32699712 http://dx.doi.org/10.7759/cureus.8717 |
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author | Htun, Zin Mar Aldawudi, Israa Katwal, Prakash C Jirjees, Srood Khan, Safeera |
author_facet | Htun, Zin Mar Aldawudi, Israa Katwal, Prakash C Jirjees, Srood Khan, Safeera |
author_sort | Htun, Zin Mar |
collection | PubMed |
description | Asthma patients have commonly been prescribed inhaled corticosteroids (ICSs) as the first line of control therapy. ICSs are associated with an increased risk of pneumonia in chronic obstructive airway disease (COPD) patients. However, the evidence remains controversial in asthma patients. Several observational studies reported an increased risk of pneumonia; however, COPD patients were not excluded clearly in these studies. In observational studies that excluded COPD patients and in randomized controlled trials, ICS use was not found to be associated with the risk of pneumonia. Hence, COPD patients should be excluded in future studies, and the currently available evidence demonstrates that ICS use is not associated with an increased risk of pneumonia in asthma patients. |
format | Online Article Text |
id | pubmed-7372200 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-73722002020-07-21 Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review Htun, Zin Mar Aldawudi, Israa Katwal, Prakash C Jirjees, Srood Khan, Safeera Cureus Internal Medicine Asthma patients have commonly been prescribed inhaled corticosteroids (ICSs) as the first line of control therapy. ICSs are associated with an increased risk of pneumonia in chronic obstructive airway disease (COPD) patients. However, the evidence remains controversial in asthma patients. Several observational studies reported an increased risk of pneumonia; however, COPD patients were not excluded clearly in these studies. In observational studies that excluded COPD patients and in randomized controlled trials, ICS use was not found to be associated with the risk of pneumonia. Hence, COPD patients should be excluded in future studies, and the currently available evidence demonstrates that ICS use is not associated with an increased risk of pneumonia in asthma patients. Cureus 2020-06-20 /pmc/articles/PMC7372200/ /pubmed/32699712 http://dx.doi.org/10.7759/cureus.8717 Text en Copyright © 2020, Htun et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Htun, Zin Mar Aldawudi, Israa Katwal, Prakash C Jirjees, Srood Khan, Safeera Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review |
title | Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review |
title_full | Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review |
title_fullStr | Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review |
title_full_unstemmed | Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review |
title_short | Inhaled Corticosteroids as an Associated Risk Factor for Asthmatic Pneumonia: A Literature Review |
title_sort | inhaled corticosteroids as an associated risk factor for asthmatic pneumonia: a literature review |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372200/ https://www.ncbi.nlm.nih.gov/pubmed/32699712 http://dx.doi.org/10.7759/cureus.8717 |
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