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Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis

BACKGROUND & AIMS: MRI-based corrected T1 (cT1) is a non-invasive method to grade the severity of steatohepatitis and liver fibrosis. We aimed to identify genetic variants influencing liver cT1 and use genetics to understand mechanisms underlying liver fibroinflammatory disease and its link with...

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Detalles Bibliográficos
Autores principales: Parisinos, Constantinos A., Wilman, Henry R., Thomas, E. Louise, Kelly, Matt, Nicholls, Rowan C., McGonigle, John, Neubauer, Stefan, Hingorani, Aroon D., Patel, Riyaz S., Hemingway, Harry, Bell, Jimmy D., Banerjee, Rajarshi, Yaghootkar, Hanieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372222/
https://www.ncbi.nlm.nih.gov/pubmed/32247823
http://dx.doi.org/10.1016/j.jhep.2020.03.032