Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

An efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed t...

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Autores principales: Moustafa, Moustafa Sherief, Mekheimer, Ramadan Ahmed, Al-Mousawi, Saleh Mohammed, Abd-Elmonem, Mohamed, El-Zorba, Hesham, Hameed, Afaf Mohamed Abdel, Mohamed, Tahany Mahmoud, Sadek, Kamal Usef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372238/
https://www.ncbi.nlm.nih.gov/pubmed/32733614
http://dx.doi.org/10.3762/bjoc.16.142
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author Moustafa, Moustafa Sherief
Mekheimer, Ramadan Ahmed
Al-Mousawi, Saleh Mohammed
Abd-Elmonem, Mohamed
El-Zorba, Hesham
Hameed, Afaf Mohamed Abdel
Mohamed, Tahany Mahmoud
Sadek, Kamal Usef
author_facet Moustafa, Moustafa Sherief
Mekheimer, Ramadan Ahmed
Al-Mousawi, Saleh Mohammed
Abd-Elmonem, Mohamed
El-Zorba, Hesham
Hameed, Afaf Mohamed Abdel
Mohamed, Tahany Mahmoud
Sadek, Kamal Usef
author_sort Moustafa, Moustafa Sherief
collection PubMed
description An efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.
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spelling pubmed-73722382020-07-29 Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines Moustafa, Moustafa Sherief Mekheimer, Ramadan Ahmed Al-Mousawi, Saleh Mohammed Abd-Elmonem, Mohamed El-Zorba, Hesham Hameed, Afaf Mohamed Abdel Mohamed, Tahany Mahmoud Sadek, Kamal Usef Beilstein J Org Chem Full Research Paper An efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products. Beilstein-Institut 2020-07-16 /pmc/articles/PMC7372238/ /pubmed/32733614 http://dx.doi.org/10.3762/bjoc.16.142 Text en Copyright © 2020, Moustafa et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Moustafa, Moustafa Sherief
Mekheimer, Ramadan Ahmed
Al-Mousawi, Saleh Mohammed
Abd-Elmonem, Mohamed
El-Zorba, Hesham
Hameed, Afaf Mohamed Abdel
Mohamed, Tahany Mahmoud
Sadek, Kamal Usef
Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
title Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
title_full Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
title_fullStr Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
title_full_unstemmed Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
title_short Microwave-assisted efficient one-pot synthesis of N(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
title_sort microwave-assisted efficient one-pot synthesis of n(2)-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372238/
https://www.ncbi.nlm.nih.gov/pubmed/32733614
http://dx.doi.org/10.3762/bjoc.16.142
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