Acute Pancreatitis Caused by Isotretinoin

Isotretinoin, a retinoid derivative, is used widely as a treatment for severe acne and other dermatological conditions. Its effect on lipid metabolism, especially the induction of hypertriglyceridemia, is well documented. There are some case reports in the literature about drug-induced pancreatitis secondary to isotretinoin. We describe another interesting case of acute pancreatitis related to severe hypertriglyceridemia due to isotretinoin.