SARS-CoV-2 IgG antibody responses in New York City

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes coronavirus disease 2019 (Covid-19) and has been declared a global pandemic by the World Health Organization. Total cases of SARS-CoV-2 worldwide exceed 10.2 million, with over 503,000 deaths recorded...

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Autores principales: Reifer, Josh, Hayum, Nosson, Heszkel, Benzion, Klagsbald, Ikey, Streva, Vincent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2020
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372255/
https://www.ncbi.nlm.nih.gov/pubmed/32777699
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115128
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author Reifer, Josh
Hayum, Nosson
Heszkel, Benzion
Klagsbald, Ikey
Streva, Vincent A.
author_facet Reifer, Josh
Hayum, Nosson
Heszkel, Benzion
Klagsbald, Ikey
Streva, Vincent A.
author_sort Reifer, Josh
collection PubMed
description Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes coronavirus disease 2019 (Covid-19) and has been declared a global pandemic by the World Health Organization. Total cases of SARS-CoV-2 worldwide exceed 10.2 million, with over 503,000 deaths recorded. Little is known about the body's immune response to SARS-CoV-2 infection. In this paper, we describe SARS-CoV-2 IgG antibody responses in 28,523 patients from the New York City metropolitan area and report a SARS-CoV-2 IgG positivity rate of 44%, indicating the widespread nature of the pandemic in the city and state of New York. Additionally, for a subset of patients, we report on the correlation between SARS-CoV-2 patient symptom severity and level of SARS-CoV-2 IgG antibody found in the patient sample.
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spelling pubmed-73722552020-07-21 SARS-CoV-2 IgG antibody responses in New York City Reifer, Josh Hayum, Nosson Heszkel, Benzion Klagsbald, Ikey Streva, Vincent A. Diagn Microbiol Infect Dis Virology Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes coronavirus disease 2019 (Covid-19) and has been declared a global pandemic by the World Health Organization. Total cases of SARS-CoV-2 worldwide exceed 10.2 million, with over 503,000 deaths recorded. Little is known about the body's immune response to SARS-CoV-2 infection. In this paper, we describe SARS-CoV-2 IgG antibody responses in 28,523 patients from the New York City metropolitan area and report a SARS-CoV-2 IgG positivity rate of 44%, indicating the widespread nature of the pandemic in the city and state of New York. Additionally, for a subset of patients, we report on the correlation between SARS-CoV-2 patient symptom severity and level of SARS-CoV-2 IgG antibody found in the patient sample. The Author(s). Published by Elsevier Inc. 2020-11 2020-07-21 /pmc/articles/PMC7372255/ /pubmed/32777699 http://dx.doi.org/10.1016/j.diagmicrobio.2020.115128 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Virology
Reifer, Josh
Hayum, Nosson
Heszkel, Benzion
Klagsbald, Ikey
Streva, Vincent A.
SARS-CoV-2 IgG antibody responses in New York City
title SARS-CoV-2 IgG antibody responses in New York City
title_full SARS-CoV-2 IgG antibody responses in New York City
title_fullStr SARS-CoV-2 IgG antibody responses in New York City
title_full_unstemmed SARS-CoV-2 IgG antibody responses in New York City
title_short SARS-CoV-2 IgG antibody responses in New York City
title_sort sars-cov-2 igg antibody responses in new york city
topic Virology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372255/
https://www.ncbi.nlm.nih.gov/pubmed/32777699
http://dx.doi.org/10.1016/j.diagmicrobio.2020.115128
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