Bioenergetic deficits in Huntington’s disease iPSC-derived neural cells and rescue with glycolytic metabolites

Altered cellular metabolism is believed to be an important contributor to pathogenesis of the neurodegenerative disorder Huntington’s disease (HD). Research has primarily focused on mitochondrial toxicity, which can cause death of the vulnerable striatal neurons, but other aspects of metabolism have...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372552/
https://www.ncbi.nlm.nih.gov/pubmed/30768179
http://dx.doi.org/10.1093/hmg/ddy430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372552/
https://www.ncbi.nlm.nih.gov/pubmed/30768179
http://dx.doi.org/10.1093/hmg/ddy430

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