The commercially available STAT3 inhibitor 5,15-diphenylporphyrin (5,15-DPP) does not directly interact with STAT3 core residues 127–722

OBJECTIVE: Target specific small molecule inhibitors has driven signaling pathway discovery and are used as common positive controls in drug discovery screens. During a biophysical screen, using surface plasmon resonance spectroscopy, of a novel small molecule library for the Signal Transducer and A...

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Detalles Bibliográficos
Autores principales: Mtwebana, Siphokazi Sinethemba, Prinsloo, Earl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372768/
https://www.ncbi.nlm.nih.gov/pubmed/32690111
http://dx.doi.org/10.1186/s13104-020-05189-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372768/
https://www.ncbi.nlm.nih.gov/pubmed/32690111
http://dx.doi.org/10.1186/s13104-020-05189-w

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