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First description of antimicrobial resistance in carbapenem-susceptible Klebsiella pneumoniae after imipenem treatment, driven by outer membrane remodeling

BACKGROUND: The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a looming threat to human health. Although there are numerous studies regarding porin alteration in association with the production of ESBLs and/or AmpC β-lactamase, a systematic study on the treatment-emergence of...

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Detalles Bibliográficos
Autores principales: Tian, Xuebin, Wang, Qiongdan, Perlaza-Jiménez, Laura, Zheng, Xiangkuo, Zhao, Yajie, Dhanasekaran, Vijay, Fang, Renchi, Li, Jiahui, Wang, Chong, Liu, Haiyang, Lithgow, Trevor, Cao, Jianming, Zhou, Tieli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372807/
https://www.ncbi.nlm.nih.gov/pubmed/32689945
http://dx.doi.org/10.1186/s12866-020-01898-1