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A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent
CASE PRESENTATION: We report for the first time a synchronous papillary and follicular thyroid carcinoma in a 12-year-old girl presenting with a large (5 cm diameter) left thyroid nodule, an increased left and right upper pole technetium tracer uptake at scintigraphy and hyperthyroidism. The uptake...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372872/ https://www.ncbi.nlm.nih.gov/pubmed/32699545 http://dx.doi.org/10.1186/s13633-020-00084-4 |
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author | Van Vlaenderen, Joke Logghe, Karl Schiettecatte, Eva Vermeersch, Hubert Huvenne, Wouter De Waele, Kathleen Van Beveren, Hanne Van Dorpe, Jo Creytens, David De Schepper, Jean |
author_facet | Van Vlaenderen, Joke Logghe, Karl Schiettecatte, Eva Vermeersch, Hubert Huvenne, Wouter De Waele, Kathleen Van Beveren, Hanne Van Dorpe, Jo Creytens, David De Schepper, Jean |
author_sort | Van Vlaenderen, Joke |
collection | PubMed |
description | CASE PRESENTATION: We report for the first time a synchronous papillary and follicular thyroid carcinoma in a 12-year-old girl presenting with a large (5 cm diameter) left thyroid nodule, an increased left and right upper pole technetium tracer uptake at scintigraphy and hyperthyroidism. The uptake at the right lobe was explained by the crossing of the left nodule to the right site of the neck at Computed Tomography (CT) scanning. BACKGROUND: Although thyroid nodules are less common in children than in adults, there is more vigilance required in children because of the higher risk of malignancy. According to literature, about 5% of the thyroid nodules in adults are malignant versus 20–26% in children. The characteristics of 9 other pediatric cases with a differentiated thyroid carcinoma presenting with a toxic nodule, which have been reported during the last 20 years, are summarized. A nodular size of more than 3.5 cm and female predominance was a common finding. CONCLUSIONS: The presence of hyperthyroidism in association with a hyperfunctioning thyroid nodule does not rule out thyroid cancer and warrants careful evaluation, even in the absence of cervical lymph node invasion. |
format | Online Article Text |
id | pubmed-7372872 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73728722020-07-21 A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent Van Vlaenderen, Joke Logghe, Karl Schiettecatte, Eva Vermeersch, Hubert Huvenne, Wouter De Waele, Kathleen Van Beveren, Hanne Van Dorpe, Jo Creytens, David De Schepper, Jean Int J Pediatr Endocrinol Case Report CASE PRESENTATION: We report for the first time a synchronous papillary and follicular thyroid carcinoma in a 12-year-old girl presenting with a large (5 cm diameter) left thyroid nodule, an increased left and right upper pole technetium tracer uptake at scintigraphy and hyperthyroidism. The uptake at the right lobe was explained by the crossing of the left nodule to the right site of the neck at Computed Tomography (CT) scanning. BACKGROUND: Although thyroid nodules are less common in children than in adults, there is more vigilance required in children because of the higher risk of malignancy. According to literature, about 5% of the thyroid nodules in adults are malignant versus 20–26% in children. The characteristics of 9 other pediatric cases with a differentiated thyroid carcinoma presenting with a toxic nodule, which have been reported during the last 20 years, are summarized. A nodular size of more than 3.5 cm and female predominance was a common finding. CONCLUSIONS: The presence of hyperthyroidism in association with a hyperfunctioning thyroid nodule does not rule out thyroid cancer and warrants careful evaluation, even in the absence of cervical lymph node invasion. BioMed Central 2020-07-21 2020 /pmc/articles/PMC7372872/ /pubmed/32699545 http://dx.doi.org/10.1186/s13633-020-00084-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Van Vlaenderen, Joke Logghe, Karl Schiettecatte, Eva Vermeersch, Hubert Huvenne, Wouter De Waele, Kathleen Van Beveren, Hanne Van Dorpe, Jo Creytens, David De Schepper, Jean A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
title | A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
title_full | A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
title_fullStr | A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
title_full_unstemmed | A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
title_short | A synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
title_sort | synchronous papillary and follicular thyroid carcinoma presenting as a large toxic nodule in a female adolescent |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372872/ https://www.ncbi.nlm.nih.gov/pubmed/32699545 http://dx.doi.org/10.1186/s13633-020-00084-4 |
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