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Long-term Safety and Tolerability of NKTR-181 in Patients with Moderate to Severe Chronic Low Back Pain or Chronic Noncancer Pain: A Phase 3 Multicenter, Open-Label, 52-Week Study (SUMMIT-08 LTS)

OBJECTIVE: To evaluate the long-term safety of NKTR-181, a novel mu-opioid receptor agonist that may have reduced human abuse potential, in patients with moderate to severe chronic low back pain (CLBP) or other chronic noncancer pain (CNP). DESIGN: Uncontrolled, multicenter, open-label, long-term st...

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Detalles Bibliográficos
Autores principales: Gudin, Jeffrey, Rauck, Richard, Argoff, Charles, Agaiby, Eva, Gimbel, Joseph, Katz, Nathaniel, Doberstein, Stephen K, Tagliaferri, Mary, Tagliaferri, Margit, Potts, Jeffrey, Wild, James, Lu, Lin, Siddhanti, Suresh, Hale, Martin, Markman, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372935/
https://www.ncbi.nlm.nih.gov/pubmed/31361019
http://dx.doi.org/10.1093/pm/pnz169