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MicroRNA-770-5p contributes to podocyte injury via targeting E2F3 in diabetic nephropathy

Diabetic nephropathy (DN) has been identified as the major cause of end-stage renal disease (ESRD) in most developed countries. MicroRNA-770-5p depletion could repress high glucose (HG)-triggered apoptosis in podocytes, and downregulation of E2F transcription factor 3 (E2F3) could facilitate podocyt...

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Detalles Bibliográficos
Autores principales: Guo, Juanjuan, Han, Jie, Liu, Jieying, Wang, Shaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7372943/
https://www.ncbi.nlm.nih.gov/pubmed/32696822
http://dx.doi.org/10.1590/1414-431X20209360