Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-β and IFN inducer

OBJECTIVES: Respiratory and intestinal tract are two primary target organs of SARS-CoV-2 infection. However, detailed characterization of the host-virus interplay in infected human lung and intestinal epithelial cells is lacking. METHODS: We utilized immunofluorescence assays, flow cytometry, and RT...

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Detalles Bibliográficos
Autores principales: Shuai, Huiping, Chu, Hin, Hou, Yuxin, Yang, Dong, Wang, Yixin, Hu, Bingjie, Huang, Xiner, Zhang, Xi, Chai, Yue, Cai, Jian-Piao, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Infection Association. Published by Elsevier Ltd. 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373021/
https://www.ncbi.nlm.nih.gov/pubmed/32707230
http://dx.doi.org/10.1016/j.jinf.2020.07.016

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