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A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies

We employ deep learning to propose an Artificial Neural Network (ANN) based and data stream guided real-time incremental learning algorithm for parameter estimation of a non-intrusive, intelligent, adaptive and online analytical model of Covid-19 disease. Modeling and simulation of such problems pos...

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Detalles Bibliográficos
Autores principales: Farooq, Junaid, Bazaz, Mohammad Abid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373073/
https://www.ncbi.nlm.nih.gov/pubmed/32834586
http://dx.doi.org/10.1016/j.chaos.2020.110148
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author Farooq, Junaid
Bazaz, Mohammad Abid
author_facet Farooq, Junaid
Bazaz, Mohammad Abid
author_sort Farooq, Junaid
collection PubMed
description We employ deep learning to propose an Artificial Neural Network (ANN) based and data stream guided real-time incremental learning algorithm for parameter estimation of a non-intrusive, intelligent, adaptive and online analytical model of Covid-19 disease. Modeling and simulation of such problems pose an additional challenge of continuously evolving training data in which the model parameters change over time depending upon external factors. Our main contribution is that in a scenario of continuously evolving training data, unlike typical deep learning techniques, this non-intrusive algorithm eliminates the need to retrain or rebuild the model from scratch every time a new training data set is received. After validating the model, we use it to study the impact of different strategies for epidemic control. Finally, we propose and simulate a strategy of controlled natural immunization through risk-based population compartmentalization (PC) wherein the population is divided in Low Risk (LR) and High Risk (HR) compartments based on risk factors (like comorbidities and age) and subjected to different disease transmission dynamics by isolating the HR compartment while allowing the LR compartment to develop natural immunity. Upon release from the preventive isolation, the HR compartment finds itself surrounded by enough number of immunized individuals to prevent the spread of infection and thus most of the deaths occurring in this group are avoided.
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spelling pubmed-73730732020-07-22 A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies Farooq, Junaid Bazaz, Mohammad Abid Chaos Solitons Fractals Article We employ deep learning to propose an Artificial Neural Network (ANN) based and data stream guided real-time incremental learning algorithm for parameter estimation of a non-intrusive, intelligent, adaptive and online analytical model of Covid-19 disease. Modeling and simulation of such problems pose an additional challenge of continuously evolving training data in which the model parameters change over time depending upon external factors. Our main contribution is that in a scenario of continuously evolving training data, unlike typical deep learning techniques, this non-intrusive algorithm eliminates the need to retrain or rebuild the model from scratch every time a new training data set is received. After validating the model, we use it to study the impact of different strategies for epidemic control. Finally, we propose and simulate a strategy of controlled natural immunization through risk-based population compartmentalization (PC) wherein the population is divided in Low Risk (LR) and High Risk (HR) compartments based on risk factors (like comorbidities and age) and subjected to different disease transmission dynamics by isolating the HR compartment while allowing the LR compartment to develop natural immunity. Upon release from the preventive isolation, the HR compartment finds itself surrounded by enough number of immunized individuals to prevent the spread of infection and thus most of the deaths occurring in this group are avoided. Elsevier Ltd. 2020-09 2020-07-21 /pmc/articles/PMC7373073/ /pubmed/32834586 http://dx.doi.org/10.1016/j.chaos.2020.110148 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Farooq, Junaid
Bazaz, Mohammad Abid
A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies
title A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies
title_full A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies
title_fullStr A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies
title_full_unstemmed A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies
title_short A novel adaptive deep learning model of Covid-19 with focus on mortality reduction strategies
title_sort novel adaptive deep learning model of covid-19 with focus on mortality reduction strategies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373073/
https://www.ncbi.nlm.nih.gov/pubmed/32834586
http://dx.doi.org/10.1016/j.chaos.2020.110148
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