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Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo

Mammographic density (MD) is a strong and independent factor for breast cancer (BC) risk and is increasingly associated with BC progression. We have previously shown in mice that high MD, which is characterized by the preponderance of a fibrous stroma, facilitates BC xenograft growth and metastasis....

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Detalles Bibliográficos
Autores principales: Huang, Xuan, Reye, Gina, Momot, Konstantin I., Blick, Tony, Lloyd, Thomas, Tilley, Wayne D., Hickey, Theresa E., Snell, Cameron E., Okolicsanyi, Rachel K., Haupt, Larisa M., Ferro, Vito, Thompson, Erik W., Hugo, Honor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373078/
https://www.ncbi.nlm.nih.gov/pubmed/32760722
http://dx.doi.org/10.3389/fcell.2020.00599