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A simple correction for COVID-19 sampling bias

COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, indivi...

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Detalles Bibliográficos
Autores principales: Díaz–Pachón, Daniel Andrés, Rao, J. Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornell University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373135/
https://www.ncbi.nlm.nih.gov/pubmed/32699814
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author Díaz–Pachón, Daniel Andrés
Rao, J. Sunil
author_facet Díaz–Pachón, Daniel Andrés
Rao, J. Sunil
author_sort Díaz–Pachón, Daniel Andrés
collection PubMed
description COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, individuals with strong symptoms are more likely to be tested than those with no symptoms. This results in biased estimates of prevalence (too high). Typical post-sampling corrections are not always possible. Here we present a simple bias correction methodology derived and adapted from a correction for publication bias in meta analysis studies. The methodology is general enough to allow a wide variety of customization making it more useful in practice. Implementation is easily done using already collected information. Via a simulation and two real datasets, we show that the bias corrections can provide dramatic reductions in estimation error.
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spelling pubmed-73731352020-07-22 A simple correction for COVID-19 sampling bias Díaz–Pachón, Daniel Andrés Rao, J. Sunil ArXiv Article COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, individuals with strong symptoms are more likely to be tested than those with no symptoms. This results in biased estimates of prevalence (too high). Typical post-sampling corrections are not always possible. Here we present a simple bias correction methodology derived and adapted from a correction for publication bias in meta analysis studies. The methodology is general enough to allow a wide variety of customization making it more useful in practice. Implementation is easily done using already collected information. Via a simulation and two real datasets, we show that the bias corrections can provide dramatic reductions in estimation error. Cornell University 2020-07-15 /pmc/articles/PMC7373135/ /pubmed/32699814 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.
spellingShingle Article
Díaz–Pachón, Daniel Andrés
Rao, J. Sunil
A simple correction for COVID-19 sampling bias
title A simple correction for COVID-19 sampling bias
title_full A simple correction for COVID-19 sampling bias
title_fullStr A simple correction for COVID-19 sampling bias
title_full_unstemmed A simple correction for COVID-19 sampling bias
title_short A simple correction for COVID-19 sampling bias
title_sort simple correction for covid-19 sampling bias
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373135/
https://www.ncbi.nlm.nih.gov/pubmed/32699814
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