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Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro

We investigated the ability of Luminore CopperTouch™ copper and copper-nickel surfaces to inactivate filoviruses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For this purpose, we compared viral titers in Vero cells from viral droplets exposed to copper surfaces for 30 min. The c...

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Detalles Bibliográficos
Autores principales: Mantlo, Emily K., Paessler, Slobodan, Seregin, Alexey, Mitchell, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373145/
https://www.ncbi.nlm.nih.gov/pubmed/32699857
http://dx.doi.org/10.1101/2020.07.05.20146043
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author Mantlo, Emily K.
Paessler, Slobodan
Seregin, Alexey
Mitchell, Alfred
author_facet Mantlo, Emily K.
Paessler, Slobodan
Seregin, Alexey
Mitchell, Alfred
author_sort Mantlo, Emily K.
collection PubMed
description We investigated the ability of Luminore CopperTouch™ copper and copper-nickel surfaces to inactivate filoviruses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For this purpose, we compared viral titers in Vero cells from viral droplets exposed to copper surfaces for 30 min. The copper and copper–nickel surfaces inactivated 99.9% of the viral titer of both Ebola and Marburg viruses. The copper surfaces also inactivated 99% of SARS-CoV-2 titers in 2 hours to close to the limit of detection. These data add Ebolavirus, Marburgvirus, and SARS-CoV-2 (COVID-19) to the list of pathogens that can be inactivated by exposure to copper ions, validating Luminore CopperTouch™ technology (currently the only Environmental Protection Agency-registered cold spray antimicrobial surface technology) as an efficacious, cost-friendly tool to improve infection control in hospitals, long-term care facilities, schools, hotels, buses, trains, airports, and other highly trafficked areas.
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spelling pubmed-73731452020-07-22 Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro Mantlo, Emily K. Paessler, Slobodan Seregin, Alexey Mitchell, Alfred medRxiv Article We investigated the ability of Luminore CopperTouch™ copper and copper-nickel surfaces to inactivate filoviruses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For this purpose, we compared viral titers in Vero cells from viral droplets exposed to copper surfaces for 30 min. The copper and copper–nickel surfaces inactivated 99.9% of the viral titer of both Ebola and Marburg viruses. The copper surfaces also inactivated 99% of SARS-CoV-2 titers in 2 hours to close to the limit of detection. These data add Ebolavirus, Marburgvirus, and SARS-CoV-2 (COVID-19) to the list of pathogens that can be inactivated by exposure to copper ions, validating Luminore CopperTouch™ technology (currently the only Environmental Protection Agency-registered cold spray antimicrobial surface technology) as an efficacious, cost-friendly tool to improve infection control in hospitals, long-term care facilities, schools, hotels, buses, trains, airports, and other highly trafficked areas. Cold Spring Harbor Laboratory 2020-07-14 /pmc/articles/PMC7373145/ /pubmed/32699857 http://dx.doi.org/10.1101/2020.07.05.20146043 Text en https://creativecommons.org/licenses/by-nd/4.0/It is made available under a CC-BY-ND 4.0 International license (https://creativecommons.org/licenses/by-nd/4.0/) .
spellingShingle Article
Mantlo, Emily K.
Paessler, Slobodan
Seregin, Alexey
Mitchell, Alfred
Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro
title Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro
title_full Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro
title_fullStr Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro
title_full_unstemmed Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro
title_short Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola, and Marburg viruses in vitro
title_sort luminore coppertouch™ surface coating effectively inactivates sars-cov-2, ebola, and marburg viruses in vitro
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373145/
https://www.ncbi.nlm.nih.gov/pubmed/32699857
http://dx.doi.org/10.1101/2020.07.05.20146043
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