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New insights on human essential genes based on integrated analysis and the construction of the HEGIAP web-based platform

Essential genes are those whose loss of function compromises organism viability or results in profound loss of fitness. Recent gene-editing technologies have provided new opportunities to characterize essential genes. Here, we present an integrated analysis that comprehensively and systematically el...

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Detalles Bibliográficos
Autores principales: Chen, Hebing, Zhang, Zhuo, Jiang, Shuai, Li, Ruijiang, Li, Wanying, Zhao, Chenghui, Hong, Hao, Huang, Xin, Li, Hao, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373178/
https://www.ncbi.nlm.nih.gov/pubmed/31504171
http://dx.doi.org/10.1093/bib/bbz072