Physiological and pathological functions of LRRK2: implications from substrate proteins

Leucine-rich repeat kinase 2 (LRRK2) encodes a 2527-amino acid (aa) protein composed of multiple functional domains, including a Ras of complex proteins (ROC)-type GTP-binding domain, a carboxyl terminal of ROC (COR) domain, a serine/threonine protein kinase domain, and several repeat domains. LRRK2...

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Detalles Bibliográficos
Autores principales: Araki, Miho, Ito, Genta, Tomita, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373236/
https://www.ncbi.nlm.nih.gov/pubmed/32714591
http://dx.doi.org/10.1042/NS20180005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373236/
https://www.ncbi.nlm.nih.gov/pubmed/32714591
http://dx.doi.org/10.1042/NS20180005

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