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Physiological and pathological functions of LRRK2: implications from substrate proteins
Leucine-rich repeat kinase 2 (LRRK2) encodes a 2527-amino acid (aa) protein composed of multiple functional domains, including a Ras of complex proteins (ROC)-type GTP-binding domain, a carboxyl terminal of ROC (COR) domain, a serine/threonine protein kinase domain, and several repeat domains. LRRK2...
Autores principales: | Araki, Miho, Ito, Genta, Tomita, Taisuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373236/ https://www.ncbi.nlm.nih.gov/pubmed/32714591 http://dx.doi.org/10.1042/NS20180005 |
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