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SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer

Breast cancer (BC) is the foremost cause of cancer related deaths in women globally. Currently there is a scarcity of reliable biomarkers for its early stage diagnosis and theranostics monitoring. Altered DNA methylation patterns leading to the silencing of tumor suppressor genes are considered as a...

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Detalles Bibliográficos
Autores principales: Shahzad, Naveed, Munir, Tehreem, Javed, Mariam, Tasneem, Fareeda, Aslam, Bilal, Ali, Moazzam, Mutahir, Zeeshan, Akhtar Ali, Muhammad, Umer, Muhammad, Ahmad, Munir, Farooq, Kokab, Hassan, Umair, Mustafa, Tanveer, Anjum, Rana Salman, Shakoori, Abdul Rauf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373276/
https://www.ncbi.nlm.nih.gov/pubmed/32692756
http://dx.doi.org/10.1371/journal.pone.0236192