Screening of tau protein kinase inhibitors in a tauopathy-relevant cell-based model of tau hyperphosphorylation and oligomerization

Tauopathies are a class of neurodegenerative disorders characterized by abnormal deposition of post-translationally modified tau protein in the human brain. Tauopathies are associated with Alzheimer’s disease (AD), chronic traumatic encephalopathy (CTE), and other diseases. Hyperphosphorylation incr...

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Detalles Bibliográficos
Autores principales: Yadikar, Hamad, Torres, Isabel, Aiello, Gabrielle, Kurup, Milin, Yang, Zhihui, Lin, Fan, Kobeissy, Firas, Yost, Richard, Wang, Kevin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373298/
https://www.ncbi.nlm.nih.gov/pubmed/32692785
http://dx.doi.org/10.1371/journal.pone.0224952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373298/
https://www.ncbi.nlm.nih.gov/pubmed/32692785
http://dx.doi.org/10.1371/journal.pone.0224952

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