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Triptonide Modulates MAPK Signaling Pathways and Exerts Anticancer Effects via ER Stress-Mediated Apoptosis Induction in Human Osteosarcoma Cells

BACKGROUND: Osteosarcoma (OS) is the most common primary malignancy arise from bone and is one of the causes of cancer-related deaths. Triptonide (TN), a diterpenoid epoxide presented in Tripterygium wilfordii, is shown to possess a broad spectrum of biological properties. METHODS: In this study, we...

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Detalles Bibliográficos
Autores principales:	Zheng, Liyun, Fang, Shiji, Hui, Junguo, Rajamanickam, Vinothkumar, Chen, Minjiang, Weng, Qiaoyou, Wu, Xulu, Zhao, Zhongwei, Ji, Jiansong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373419/ https://www.ncbi.nlm.nih.gov/pubmed/32765093 http://dx.doi.org/10.2147/CMAR.S258203

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