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Synergistic Effect of Bypassing Agents and Sequence Identical Analogue of Emicizumab and Fibrin Clot Structure in the In Vitro Model of Hemophilia A

Development of inhibitors to factor VIII (FVIII) occurs in approximately 30% of severe hemophilia A (HA) patients. These patients are treated with bypassing agents (activated prothrombin complex concentrate [aPCC] and recombinant activated FVII-rFVIIa). Recently, a bispecific FIX/FIXa- and FX/FXa-di...

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Detalles Bibliográficos
Autores principales:	Zong, Yanan, Antovic, Aleksandra, Soutari, Nida Mahmoud Hourani, Antovic, Jovan, Pruner, Iva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373667/ https://www.ncbi.nlm.nih.gov/pubmed/32704613 http://dx.doi.org/10.1055/s-0040-1710032

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