Cargando…

Genomic Analysis Identifies Mutations Concerning Drug-Resistance and Beijing Genotype in Multidrug-Resistant Mycobacterium tuberculosis Isolated From China

Development of modern genomics provides us an effective method to understand the molecular mechanism of drug resistance and diagnose drug-resistant Mycobacterium tuberculosis. In this study, mutations in 18 genes or intergenic regions acquired by whole-genome sequencing (WGS) of 183 clinical M. tube...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wan, Li, Liu, Haican, Li, Machao, Jiang, Yi, Zhao, Xiuqin, Liu, Zhiguang, Wan, Kanglin, Li, Guilian, Guan, Cha-xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373740/ https://www.ncbi.nlm.nih.gov/pubmed/32760357 http://dx.doi.org/10.3389/fmicb.2020.01444

Ejemplares similares

Association of Single-Nucleotide Polymorphisms in the VDR Gene with Tuberculosis and Infection of Beijing Genotype Mycobacterium tuberculosis
por: Yu, Jinjie, et al.
Publicado: (2023)

Detection of Resistance to Fluoroquinolones and Second-Line Injectable Drugs Among Mycobacterium tuberculosis by a Reverse Dot Blot Hybridization Assay
por: Li, Guilian, et al.
Publicado: (2020)

Single Nucleotide Polymorphism in Ag85 Genes of Mycobacterium Tuberculosis Complex: Analysis of 178 Clinical Isolates from China and 13 BCG strains
por: Jiang, Yi, et al.
Publicado: (2015)

Prevalence and Molecular Characteristics Based on Whole Genome Sequencing of Mycobacterium tuberculosis Resistant to Four Anti-Tuberculosis Drugs from Southern Xinjiang, China
por: Anwaierjiang, Aiketaguli, et al.
Publicado: (2021)

A New Single Gene Differential Biomarker for Mycobacterium tuberculosis Complex and Non-tuberculosis Mycobacteria
por: Zhou, Lei, et al.
Publicado: (2019)

Efflux Pump Gene Expression in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates
por: Li, Guilian, et al.
Publicado: (2015)

Genetic Characterization Conferred Co-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Isolates from Southern Xinjiang, China
por: Cao, Bin, et al.
Publicado: (2023)

Comparative Analysis of Human B Cell Epitopes Based on BCG Genomes
por: Li, Machao, et al.
Publicado: (2016)

Association of Mannose-Binding Lectin 2 Gene Polymorphism with Tuberculosis Based on Mycobacterium tuberculosis Lineages
por: Liu, Mengwen, et al.
Publicado: (2022)

A novel multistage antigens ERA005f confer protection against Mycobacterium tuberculosis by driving Th-1 and Th-17 type T cell immune responses
por: Fan, Xueting, et al.
Publicado: (2023)

Molecular Epidemiology of Clinical Mycobacterium tuberculosis Isolates from Southern Xinjiang, China Using Spoligotyping and 15-Locus MIRU-VNTR Typing
por: Yin, Chunjie, et al.
Publicado: (2023)

Epidemiological characteristics and trends of notifiable infectious diseases in China from 1986 to 2016
por: Jiang, Yi, et al.
Publicado: (2020)

Locked Nucleic Acid Probe-Based Real-Time PCR Assay for the Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis
por: Zhao, Yong, et al.
Publicado: (2015)

Correction: Locked Nucleic Acid Probe-Based Real-Time PCR Assay for the Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis
por: Zhao, Yong, et al.
Publicado: (2016)

First Insight into the Genotypic Diversity of Clinical Mycobacterium tuberculosis Isolates from Gansu Province, China
por: Liu, Jie, et al.
Publicado: (2014)

Investigation on Mycobacterium tuberculosis Diversity in China and the Origin of the Beijing Clade
por: Wan, Kanglin, et al.
Publicado: (2011)

Genotypic Diversity of Mycobacterium tuberculosis Clinical Isolates in the Multiethnic Area of the Xinjiang Uygur Autonomous Region in China
por: Liu, Jie, et al.
Publicado: (2017)

In Vitro Activity of β-Lactams in Combination with β-Lactamase Inhibitors against Mycobacterium tuberculosis Clinical Isolates
por: Li, Fu, et al.
Publicado: (2018)

A novel multi-component protein vaccine ECP001 containing a protein polypeptide antigen nPstS1 riching in T-cell epitopes showed good immunogenicity and protection in mice
por: Yu, Jinjie, et al.
Publicado: (2023)

MicroRNA signatures from multidrug-resistant Mycobacterium tuberculosis
por: REN, NA, et al.
Publicado: (2015)

Drug Susceptibility Testing of 31 Antimicrobial Agents on Rapidly Growing Mycobacteria Isolates from China
por: Pang, Hui, et al.
Publicado: (2015)

Genetic diversity of Mycobacterium tuberculosis isolates from Beijing, China assessed by Spoligotyping, LSPs and VNTR profiles
por: Lu, Bing, et al.
Publicado: (2012)

Genetic Diversity of Mycobacterium tuberculosis Isolates from Tibetans in Tibet, China
por: Dong, Haiyan, et al.
Publicado: (2012)

Characterization of Mycobacterium tuberculosis isolates from Hebei, China: genotypes and drug susceptibility phenotypes
por: Li, Yanan, et al.
Publicado: (2016)

Beijing/W Genotype Mycobacterium tuberculosis and Drug Resistance
Publicado: (2006)

Identification and evaluation of the novel immunodominant antigen Rv2351c from Mycobacterium tuberculosis
por: Wang, Xuezhi, et al.
Publicado: (2017)

Polymorphism of MPT64 and PstS1 in Mycobacterium tuberculosis is not likely to affect relative immune reaction in human
por: Xiao, Tongyang, et al.
Publicado: (2019)

Phylogenetic relationships of Mycobacterium tuberculosis isolates in Poland: The emergence of Beijing genotype among multidrug-resistant cases
por: Bakuła, Zofia, et al.
Publicado: (2023)

A Multistage Antigen Complex Epera013 Promotes Efficient and Comprehensive Immune Responses in BALB/c Mice
por: Qian, Chengyu, et al.
Publicado: (2023)

Mycobacterium tuberculosis Beijing Genotype Resistance to Transient Rifampin Exposure
por: den Hertog, Alice L., et al.
Publicado: (2014)

Antimicrobial Susceptibility of Standard Strains of Nontuberculous Mycobacteria by Microplate Alamar Blue Assay
por: Li, Guilian, et al.
Publicado: (2013)

Genetic Diversity of Mycobacterium tuberculosis from Guadalajara, Mexico and Identification of a Rare Multidrug Resistant Beijing Genotype
por: Flores-Treviño, Samantha, et al.
Publicado: (2015)

Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015
por: Merker, Matthias, et al.
Publicado: (2020)

High Immunogenicity of a T-Cell Epitope-Rich Recombinant Protein Rv1566c-444 From Mycobacterium tuberculosis in Immunized BALB/c Mice, Despite Its Low Diagnostic Sensitivity
por: Luan, Xiuli, et al.
Publicado: (2022)

Drug Resistant Mycobacterium tuberculosis of the Beijing Genotype Does Not Spread in Sweden
por: Ghebremichael, Solomon, et al.
Publicado: (2010)

A Country-Wide Study of Spoligotype and Drug Resistance Characteristics of Mycobacterium tuberculosis Isolates from Children in China
por: Jiao, Weiwei, et al.
Publicado: (2013)

Mycobacterium tuberculosis Beijing Genotype(1)
por: Lillebaek, Troels, et al.
Publicado: (2003)

Mycobacterium tuberculosis Beijing Genotype, the Netherlands
por: Borgdorff, Martien W., et al.
Publicado: (2003)

Mycobacterium tuberculosis Beijing genotype family strain isolated from naturally infected plateau zokor (Myospalax baileyi) in China
por: Sun, Lin, et al.
Publicado: (2017)

Transmission and Drug Resistance Genotype of Multidrug-Resistant or Rifampicin-Resistant Mycobacterium tuberculosis in Chongqing, China
por: Zhao, Bing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0b725tsjrja6icec15abfedp6u