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Contemporary use of devices in chronic heart failure in the Netherlands

AIMS: Despite previous surveys regarding device implantation rates in heart failure (HF), insight into the real‐world management with devices is scarce. Therefore, we investigated device implantation rates in HF with reduced left ventricular ejection fraction (LVEF) in 34 Dutch centres. METHODS AND...

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Autores principales: Raafs, Anne G., Linssen, Gerard C.M., Brugts, Jasper J., Erol‐Yilmaz, Ayten, Plomp, Jacobus, Smits, Jeroen P.P., Nagelsmit, Michiel J., Oortman, Remko M., Hoes, Arno W., Brunner‐LaRocca, Hans‐Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373943/
https://www.ncbi.nlm.nih.gov/pubmed/32395914
http://dx.doi.org/10.1002/ehf2.12740
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author Raafs, Anne G.
Linssen, Gerard C.M.
Brugts, Jasper J.
Erol‐Yilmaz, Ayten
Plomp, Jacobus
Smits, Jeroen P.P.
Nagelsmit, Michiel J.
Oortman, Remko M.
Hoes, Arno W.
Brunner‐LaRocca, Hans‐Peter
author_facet Raafs, Anne G.
Linssen, Gerard C.M.
Brugts, Jasper J.
Erol‐Yilmaz, Ayten
Plomp, Jacobus
Smits, Jeroen P.P.
Nagelsmit, Michiel J.
Oortman, Remko M.
Hoes, Arno W.
Brunner‐LaRocca, Hans‐Peter
author_sort Raafs, Anne G.
collection PubMed
description AIMS: Despite previous surveys regarding device implantation rates in heart failure (HF), insight into the real‐world management with devices is scarce. Therefore, we investigated device implantation rates in HF with reduced left ventricular ejection fraction (LVEF) in 34 Dutch centres. METHODS AND RESULTS: A cross‐sectional outpatient registry was conducted in 6666 patients with LVEF < 50% and with information about device implantation available [74 (66–81) years of age; 64% male]. Patients were classified into conventional pacemakers (PM, n = 562), implantable cardioverter defibrillators (ICD, n = 1165), and cardiac resynchronization therapy with defibrillator function (CRT‐D, n = 885) or pacemaker function only (CRT‐P, n = 248), or no device (n = 3806). Centres were divided into ICD‐implanting and CRT‐implanting and referral centres. Overall, 17.5% had an ICD, 13.3% CRT‐D, 3.7% CRT‐P, and 8.4% PM. Of those with LVEF ≤ 30%, 42.5% had ICD or CRT‐D therapy. A large variation in implantation rates existed between centres: 3–51% for ICD therapy, 0.3–44% for CRT‐D therapy, 0–11% for CRT‐P therapy, and 0–25% PM therapy. Implantation centres showed higher implantation rates of ICD, CRT‐D, and CRT‐P compared with referral centres [36% vs. 25% for defibrillators (ICD or CRT‐D) and 17% vs. 9% for CRT devices (CRT‐D or CRT‐P), respectively, P < 0.001], independently of other factors. A large number of clinical factors were predictive for device usage. Among other, LVEF < 40% and male sex were independent positive predictors for ICD/CRT‐D use [odds ratio (OR) = 3.33, P < 0.001; OR = 1.87, P = 0.019, respectively]. Older age was independently associated with less ICD/CRT‐D (OR = 0.96 per year, P < 0.001) and more CRT‐P/PM use (OR = 1.03 per year, P = 0.006). CONCLUSIONS: In this large Dutch HF registry, less than half of the patients with reduced LVEF received an ICD or CRT, even if LVEF was ≤30%, and a large variation between centres existed. Patients from implantation centres had more often ICD or CRT. More uniformity regarding guideline‐based use of device therapy in clinical practice is needed.
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spelling pubmed-73739432020-07-22 Contemporary use of devices in chronic heart failure in the Netherlands Raafs, Anne G. Linssen, Gerard C.M. Brugts, Jasper J. Erol‐Yilmaz, Ayten Plomp, Jacobus Smits, Jeroen P.P. Nagelsmit, Michiel J. Oortman, Remko M. Hoes, Arno W. Brunner‐LaRocca, Hans‐Peter ESC Heart Fail Original Research Articles AIMS: Despite previous surveys regarding device implantation rates in heart failure (HF), insight into the real‐world management with devices is scarce. Therefore, we investigated device implantation rates in HF with reduced left ventricular ejection fraction (LVEF) in 34 Dutch centres. METHODS AND RESULTS: A cross‐sectional outpatient registry was conducted in 6666 patients with LVEF < 50% and with information about device implantation available [74 (66–81) years of age; 64% male]. Patients were classified into conventional pacemakers (PM, n = 562), implantable cardioverter defibrillators (ICD, n = 1165), and cardiac resynchronization therapy with defibrillator function (CRT‐D, n = 885) or pacemaker function only (CRT‐P, n = 248), or no device (n = 3806). Centres were divided into ICD‐implanting and CRT‐implanting and referral centres. Overall, 17.5% had an ICD, 13.3% CRT‐D, 3.7% CRT‐P, and 8.4% PM. Of those with LVEF ≤ 30%, 42.5% had ICD or CRT‐D therapy. A large variation in implantation rates existed between centres: 3–51% for ICD therapy, 0.3–44% for CRT‐D therapy, 0–11% for CRT‐P therapy, and 0–25% PM therapy. Implantation centres showed higher implantation rates of ICD, CRT‐D, and CRT‐P compared with referral centres [36% vs. 25% for defibrillators (ICD or CRT‐D) and 17% vs. 9% for CRT devices (CRT‐D or CRT‐P), respectively, P < 0.001], independently of other factors. A large number of clinical factors were predictive for device usage. Among other, LVEF < 40% and male sex were independent positive predictors for ICD/CRT‐D use [odds ratio (OR) = 3.33, P < 0.001; OR = 1.87, P = 0.019, respectively]. Older age was independently associated with less ICD/CRT‐D (OR = 0.96 per year, P < 0.001) and more CRT‐P/PM use (OR = 1.03 per year, P = 0.006). CONCLUSIONS: In this large Dutch HF registry, less than half of the patients with reduced LVEF received an ICD or CRT, even if LVEF was ≤30%, and a large variation between centres existed. Patients from implantation centres had more often ICD or CRT. More uniformity regarding guideline‐based use of device therapy in clinical practice is needed. John Wiley and Sons Inc. 2020-05-12 /pmc/articles/PMC7373943/ /pubmed/32395914 http://dx.doi.org/10.1002/ehf2.12740 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research Articles
Raafs, Anne G.
Linssen, Gerard C.M.
Brugts, Jasper J.
Erol‐Yilmaz, Ayten
Plomp, Jacobus
Smits, Jeroen P.P.
Nagelsmit, Michiel J.
Oortman, Remko M.
Hoes, Arno W.
Brunner‐LaRocca, Hans‐Peter
Contemporary use of devices in chronic heart failure in the Netherlands
title Contemporary use of devices in chronic heart failure in the Netherlands
title_full Contemporary use of devices in chronic heart failure in the Netherlands
title_fullStr Contemporary use of devices in chronic heart failure in the Netherlands
title_full_unstemmed Contemporary use of devices in chronic heart failure in the Netherlands
title_short Contemporary use of devices in chronic heart failure in the Netherlands
title_sort contemporary use of devices in chronic heart failure in the netherlands
topic Original Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373943/
https://www.ncbi.nlm.nih.gov/pubmed/32395914
http://dx.doi.org/10.1002/ehf2.12740
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