Cargando…
A generalizable data-driven multicellular model of pancreatic ductal adenocarcinoma
BACKGROUND: Mechanistic models, when combined with pertinent data, can improve our knowledge regarding important molecular and cellular mechanisms found in cancer. These models make the prediction of tissue-level response to drug treatment possible, which can lead to new therapies and improved patie...
Autores principales: | Aguilar, Boris, Gibbs, David L, Reiss, David J, McConnell, Mark, Danziger, Samuel A, Dervan, Andrew, Trotter, Matthew, Bassett, Douglas, Hershberg, Robert, Ratushny, Alexander V, Shmulevich, Ilya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374045/ https://www.ncbi.nlm.nih.gov/pubmed/32696951 http://dx.doi.org/10.1093/gigascience/giaa075 |
Ejemplares similares
-
ADAPTS: Automated deconvolution augmentation of profiles for tissue specific cells
por: Danziger, Samuel A., et al.
Publicado: (2019) -
Patient-Specific Cell Communication Networks Associate With Disease Progression in Cancer
por: Gibbs, David L., et al.
Publicado: (2021) -
Computational capabilities of a multicellular reservoir computing system
por: Nikolić, Vladimir, et al.
Publicado: (2023) -
Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma
por: Wall, Matthew A., et al.
Publicado: (2021) -
Trade-off between Responsiveness and Noise Suppression in Biomolecular System Responses to Environmental Cues
por: Ratushny, Alexander V., et al.
Publicado: (2011)