UGT2B17 modifies drug response in chronic lymphocytic leukaemia

BACKGROUND: High UGT2B17 is associated with poor prognosis in untreated chronic lymphocytic leukaemia (CLL) patients and its expression is induced in non-responders to fludarabine-containing regimens. We examined whether UGT2B17, the predominant lymphoid glucuronosyltransferase, affects leukaemic dr...

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Detalles Bibliográficos
Autores principales: Allain, Eric P., Rouleau, Michèle, Vanura, Katrina, Tremblay, Sophie, Vaillancourt, Joanie, Bat, Vincent, Caron, Patrick, Villeneuve, Lyne, Labriet, Adrien, Turcotte, Véronique, Le, Trang, Shehata, Medhat, Schnabl, Susanne, Demirtas, Dita, Hubmann, Rainer, Joly-Beauparlant, Charles, Droit, Arnaud, Jäger, Ulrich, Staber, Philipp B., Lévesque, Eric, Guillemette, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374097/
https://www.ncbi.nlm.nih.gov/pubmed/32418995
http://dx.doi.org/10.1038/s41416-020-0887-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374097/
https://www.ncbi.nlm.nih.gov/pubmed/32418995
http://dx.doi.org/10.1038/s41416-020-0887-6

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