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Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations
Numerous studies of knockout mice find impacts on microbiota composition that influence host phenotype. However, such differences can vanish when KO mice are compared directly to WT littermates, suggesting these differences do not reflect the genetic deletion per se but microbiota composition drifti...
Autores principales: | Viennois, Emilie, Pujada, Adani, Sung, Junsik, Yang, Chunhua, Gewirtz, Andrew T., Chassaing, Benoit, Merlin, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374158/ https://www.ncbi.nlm.nih.gov/pubmed/32694535 http://dx.doi.org/10.1038/s41522-020-0137-y |
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