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Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations

Numerous studies of knockout mice find impacts on microbiota composition that influence host phenotype. However, such differences can vanish when KO mice are compared directly to WT littermates, suggesting these differences do not reflect the genetic deletion per se but microbiota composition drifti...

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Detalles Bibliográficos
Autores principales: Viennois, Emilie, Pujada, Adani, Sung, Junsik, Yang, Chunhua, Gewirtz, Andrew T., Chassaing, Benoit, Merlin, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374158/
https://www.ncbi.nlm.nih.gov/pubmed/32694535
http://dx.doi.org/10.1038/s41522-020-0137-y

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