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ColoType: a forty gene signature for consensus molecular subtyping of colorectal cancer tumors using whole-genome assay or targeted RNA-sequencing
Colorectal cancer (CRC) tumors can be partitioned into four biologically distinct consensus molecular subtypes (CMS1-4) using gene expression. Evidence is accumulating that tumors in different subtypes are likely to respond differently to treatments. However, to date, there is no clinical diagnostic...
Autores principales: | Buechler, Steven A., Stephens, Melissa T., Hummon, Amanda B., Ludwig, Katelyn, Cannon, Emily, Carter, Tonia C., Resnick, Jeffrey, Gökmen-Polar, Yesim, Badve, Sunil S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374173/ https://www.ncbi.nlm.nih.gov/pubmed/32694712 http://dx.doi.org/10.1038/s41598-020-69083-y |
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