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Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review

MATERIALS AND METHODS: The electronic databases PubMed and Google Scholar were used to search the literature for relevant studies after applying specific inclusion and exclusion criteria. Studies that fulfilled both the inclusion and exclusion criteria were included in this systematic review. The se...

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Autores principales: Alghamdi, Faisal T., Alqurashi, Alaa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374232/
https://www.ncbi.nlm.nih.gov/pubmed/32765197
http://dx.doi.org/10.1155/2020/7954357
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author Alghamdi, Faisal T.
Alqurashi, Alaa E.
author_facet Alghamdi, Faisal T.
Alqurashi, Alaa E.
author_sort Alghamdi, Faisal T.
collection PubMed
description MATERIALS AND METHODS: The electronic databases PubMed and Google Scholar were used to search the literature for relevant studies after applying specific inclusion and exclusion criteria. Studies that fulfilled both the inclusion and exclusion criteria were included in this systematic review. The search was conducted by two independent reviewers following the PRISMA guidelines. RESULTS: Only 46 studies that fulfilled both the inclusion and exclusion criteria, which were conducted within the last 10 years, were included in this systematic review. These studies investigated different aspects of regenerative endodontic therapy including different types of scaffolds, intracanal medications, pulpal space/barriers, root maturation stage, follow-up duration, and updated studies on their use in the management of immature necrotic permanent teeth. CONCLUSIONS: This review concluded the compiled data observed that endodontic regenerative therapy was more efficient in treating immature necrotic permanent teeth and offered a greater advantage that should lead to wider acceptance among endodontists for effective results compared to different treatment options. However, more clinical trials with a standardized protocol and defined clinical, radiographic, and histopathological outcomes with longer follow-up periods are warranted.
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spelling pubmed-73742322020-08-05 Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review Alghamdi, Faisal T. Alqurashi, Alaa E. ScientificWorldJournal Review Article MATERIALS AND METHODS: The electronic databases PubMed and Google Scholar were used to search the literature for relevant studies after applying specific inclusion and exclusion criteria. Studies that fulfilled both the inclusion and exclusion criteria were included in this systematic review. The search was conducted by two independent reviewers following the PRISMA guidelines. RESULTS: Only 46 studies that fulfilled both the inclusion and exclusion criteria, which were conducted within the last 10 years, were included in this systematic review. These studies investigated different aspects of regenerative endodontic therapy including different types of scaffolds, intracanal medications, pulpal space/barriers, root maturation stage, follow-up duration, and updated studies on their use in the management of immature necrotic permanent teeth. CONCLUSIONS: This review concluded the compiled data observed that endodontic regenerative therapy was more efficient in treating immature necrotic permanent teeth and offered a greater advantage that should lead to wider acceptance among endodontists for effective results compared to different treatment options. However, more clinical trials with a standardized protocol and defined clinical, radiographic, and histopathological outcomes with longer follow-up periods are warranted. Hindawi 2020-07-13 /pmc/articles/PMC7374232/ /pubmed/32765197 http://dx.doi.org/10.1155/2020/7954357 Text en Copyright © 2020 Faisal T. Alghamdi and Alaa E. Alqurashi. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Alghamdi, Faisal T.
Alqurashi, Alaa E.
Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review
title Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review
title_full Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review
title_fullStr Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review
title_full_unstemmed Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review
title_short Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review
title_sort regenerative endodontic therapy in the management of immature necrotic permanent dentition: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374232/
https://www.ncbi.nlm.nih.gov/pubmed/32765197
http://dx.doi.org/10.1155/2020/7954357
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