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En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge

Liposarcomas are exceedingly rare entities that evoke malignant transformation of connective tissue and fat cells. These tumours occur throughout the soft tissues of the body, afflicting a myriad of regions. In the adult population, liposarcomas represent the most prevalent subtype of sarcomas, and...

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Autores principales: Almas, Talal, Ullah, Muneeb, Ehtesham, Maryam, Akbar, Absam, Khan, Muhammad Kashif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374261/
https://www.ncbi.nlm.nih.gov/pubmed/32714670
http://dx.doi.org/10.7759/cureus.8730
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author Almas, Talal
Ullah, Muneeb
Ehtesham, Maryam
Akbar, Absam
Khan, Muhammad Kashif
author_facet Almas, Talal
Ullah, Muneeb
Ehtesham, Maryam
Akbar, Absam
Khan, Muhammad Kashif
author_sort Almas, Talal
collection PubMed
description Liposarcomas are exceedingly rare entities that evoke malignant transformation of connective tissue and fat cells. These tumours occur throughout the soft tissues of the body, afflicting a myriad of regions. In the adult population, liposarcomas represent the most prevalent subtype of sarcomas, and often arise de novo. Retroperitoneal liposarcomas (RLS) are a ubiquitous subset of sarcomas that, due to their deep location in the hollow abdomen, can grow to astronomical proportions before manifesting any noticeable symptoms; a prompt diagnosis of RLS is therefore often rendered dilatory. We hereby delineate the case of a 43-year-old woman who presented with vague left hemiabdominal distention and discomfort. A subsequent computed tomography scan divulged a giant retroperitoneal growth impaling on and thus displacing the pancreas. A compartmental, en bloc resection was performed, with subsequent histopathology of the excised specimen revealing a well-differentiated liposarcoma. The surgical intervention was curative and led to an uneventful recovery. This paper highlights the pertinence of surgical management as an appropriate treatment modality for a complete resection of RLS. 
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spelling pubmed-73742612020-07-23 En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge Almas, Talal Ullah, Muneeb Ehtesham, Maryam Akbar, Absam Khan, Muhammad Kashif Cureus Pathology Liposarcomas are exceedingly rare entities that evoke malignant transformation of connective tissue and fat cells. These tumours occur throughout the soft tissues of the body, afflicting a myriad of regions. In the adult population, liposarcomas represent the most prevalent subtype of sarcomas, and often arise de novo. Retroperitoneal liposarcomas (RLS) are a ubiquitous subset of sarcomas that, due to their deep location in the hollow abdomen, can grow to astronomical proportions before manifesting any noticeable symptoms; a prompt diagnosis of RLS is therefore often rendered dilatory. We hereby delineate the case of a 43-year-old woman who presented with vague left hemiabdominal distention and discomfort. A subsequent computed tomography scan divulged a giant retroperitoneal growth impaling on and thus displacing the pancreas. A compartmental, en bloc resection was performed, with subsequent histopathology of the excised specimen revealing a well-differentiated liposarcoma. The surgical intervention was curative and led to an uneventful recovery. This paper highlights the pertinence of surgical management as an appropriate treatment modality for a complete resection of RLS.  Cureus 2020-06-20 /pmc/articles/PMC7374261/ /pubmed/32714670 http://dx.doi.org/10.7759/cureus.8730 Text en Copyright © 2020, Almas et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Almas, Talal
Ullah, Muneeb
Ehtesham, Maryam
Akbar, Absam
Khan, Muhammad Kashif
En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge
title En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge
title_full En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge
title_fullStr En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge
title_full_unstemmed En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge
title_short En Bloc Resection of a Giant Retroperitoneal Liposarcoma: A Surgical Challenge
title_sort en bloc resection of a giant retroperitoneal liposarcoma: a surgical challenge
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374261/
https://www.ncbi.nlm.nih.gov/pubmed/32714670
http://dx.doi.org/10.7759/cureus.8730
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