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Blockade of the TLR4–MD2 complex lowers blood pressure and improves vascular function in a murine model of type 1 diabetes
While the pathogenesis of diabetes-induced high blood pressure (BP) is not entirely clear, current evidence suggests that Toll-like receptor 4 (TLR4) is a key player in the mechanisms associated with hypertension. However, it is unknown whether this receptor affects BP under type 1 diabetes. Likewis...
Autores principales: | de Oliveira, Amanda Almeida, Faustino, Josemar, Webb, R. Clinton, Nunes, Kenia Pedrosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374604/ https://www.ncbi.nlm.nih.gov/pubmed/32694567 http://dx.doi.org/10.1038/s41598-020-68919-x |
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