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Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China

This study was aimed to describe the standardized treatment rate of syphilis-infected pregnant women in Hunan province and to explore the determinants for standardized treatment. All syphilis-infected pregnant women registered in the Information System of Prevention of Mother-to-Child Transmission o...

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Autores principales: Li, Huixia, Tan, Jingjing, Luo, Zhongwen, Zheng, Jianfei, Huang, Guangwen, Xiao, Juan, Huang, Qun, Feng, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374608/
https://www.ncbi.nlm.nih.gov/pubmed/32694571
http://dx.doi.org/10.1038/s41598-020-69070-3
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author Li, Huixia
Tan, Jingjing
Luo, Zhongwen
Zheng, Jianfei
Huang, Guangwen
Xiao, Juan
Huang, Qun
Feng, Na
author_facet Li, Huixia
Tan, Jingjing
Luo, Zhongwen
Zheng, Jianfei
Huang, Guangwen
Xiao, Juan
Huang, Qun
Feng, Na
author_sort Li, Huixia
collection PubMed
description This study was aimed to describe the standardized treatment rate of syphilis-infected pregnant women in Hunan province and to explore the determinants for standardized treatment. All syphilis-infected pregnant women registered in the Information System of Prevention of Mother-to-Child Transmission of Syphilis Management (IPMTCT) in Hunan between January 2015 and December 2018 were included in this study. Among 9,059 pregnant women with syphilis, 7,797 received syphilis treatment, with a treatment rate of 86.1%, and 4,963 underwent standardized syphilis treatment, with an average standardized treatment rate of 54.8%. The facilitators for the standardized treatment included abnormal reproductive histories (aOR = 1.15, 95%CI:1.03–1.28), time of first prenatal care within 1–12 weeks (aOR = 5.17, 95%CI:4.19–6.37) or within 13–27 weeks (aOR = 5.56, 95%CI:4.46–6.92), previous syphilis infection (aOR = 1.64, 95%CI: 1.48–1.81), and definite syphilis infection status of sexual partner (negative: aOR = 1.73, 95%CI:1.57–1.91; positive: aOR = 1.62, 95%CI:1.34–1.95). The barriers included marital status being unmarried/divorced/widowed (aOR = 0.81, 95%CI: 0.65–0.99), pluripara (aOR = 0.58, 95%CI: 0.46–0.74), number of children ≥ 2 (aOR = 0.45, 95%CI: 0.35–0.57), and syphilis clinical stage being primary/secondary/tertiary (aOR = 0.72, 95%CI: 0.58–0.88) or unclear (aOR = 0.78, 95%CI: 0.70–0.86). Though the treatment rate of syphilis-infected pregnant women was high, the standardized treatment rate was low. The facilitators and barriers on standardized treatment of gestational syphilis were identified at the patient level.
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spelling pubmed-73746082020-07-22 Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China Li, Huixia Tan, Jingjing Luo, Zhongwen Zheng, Jianfei Huang, Guangwen Xiao, Juan Huang, Qun Feng, Na Sci Rep Article This study was aimed to describe the standardized treatment rate of syphilis-infected pregnant women in Hunan province and to explore the determinants for standardized treatment. All syphilis-infected pregnant women registered in the Information System of Prevention of Mother-to-Child Transmission of Syphilis Management (IPMTCT) in Hunan between January 2015 and December 2018 were included in this study. Among 9,059 pregnant women with syphilis, 7,797 received syphilis treatment, with a treatment rate of 86.1%, and 4,963 underwent standardized syphilis treatment, with an average standardized treatment rate of 54.8%. The facilitators for the standardized treatment included abnormal reproductive histories (aOR = 1.15, 95%CI:1.03–1.28), time of first prenatal care within 1–12 weeks (aOR = 5.17, 95%CI:4.19–6.37) or within 13–27 weeks (aOR = 5.56, 95%CI:4.46–6.92), previous syphilis infection (aOR = 1.64, 95%CI: 1.48–1.81), and definite syphilis infection status of sexual partner (negative: aOR = 1.73, 95%CI:1.57–1.91; positive: aOR = 1.62, 95%CI:1.34–1.95). The barriers included marital status being unmarried/divorced/widowed (aOR = 0.81, 95%CI: 0.65–0.99), pluripara (aOR = 0.58, 95%CI: 0.46–0.74), number of children ≥ 2 (aOR = 0.45, 95%CI: 0.35–0.57), and syphilis clinical stage being primary/secondary/tertiary (aOR = 0.72, 95%CI: 0.58–0.88) or unclear (aOR = 0.78, 95%CI: 0.70–0.86). Though the treatment rate of syphilis-infected pregnant women was high, the standardized treatment rate was low. The facilitators and barriers on standardized treatment of gestational syphilis were identified at the patient level. Nature Publishing Group UK 2020-07-21 /pmc/articles/PMC7374608/ /pubmed/32694571 http://dx.doi.org/10.1038/s41598-020-69070-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Li, Huixia
Tan, Jingjing
Luo, Zhongwen
Zheng, Jianfei
Huang, Guangwen
Xiao, Juan
Huang, Qun
Feng, Na
Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China
title Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China
title_full Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China
title_fullStr Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China
title_full_unstemmed Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China
title_short Standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in Hunan, China
title_sort standardized treatment and determinants on 9,059 syphilis-infected pregnant women during 2015–2018 in hunan, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374608/
https://www.ncbi.nlm.nih.gov/pubmed/32694571
http://dx.doi.org/10.1038/s41598-020-69070-3
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