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Exploiting phage receptor binding proteins to enable endolysins to kill Gram-negative bacteria
Bacteriophage-encoded endolysins degrading the bacterial peptidoglycan are promising antibacterials for combating antibiotic-resistant bacteria. However, endolysins have limited use against Gram-negative bacteria, since the outer membrane prevents access to the peptidoglycan. Here, we present Innoly...
Autores principales: | Zampara, Athina, Sørensen, Martine C. Holst, Grimon, Dennis, Antenucci, Fabio, Vitt, Amira Ruslanovna, Bortolaia, Valeria, Briers, Yves, Brøndsted, Lone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374709/ https://www.ncbi.nlm.nih.gov/pubmed/32694655 http://dx.doi.org/10.1038/s41598-020-68983-3 |
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