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Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?
BACKGROUND: Immune checkpoint inhibitors (ICI) improve survival but cause immune-related adverse events (irAE). We sought to determine if CTCAE classification, IBD biomarkers/endoscopic/histological scores correlate with irAE colitis outcomes. METHODS: A dual-centre retrospective study was performed...
Autores principales: | Cheung, Vincent Ting Fung, Gupta, Tarun, Olsson-Brown, Anna, Subramanian, Sreedhar, Sasson, Sarah Christina, Heseltine, Jonathan, Fryer, Eve, Collantes, Elena, Sacco, Joseph J., Pirmohamed, Munir, Simmons, Alison, Klenerman, Paul, Tuthill, Mark, Protheroe, Andrew S., Chitnis, Meenali, Fairfax, Benjamin Peter, Payne, Miranda Jane, Middleton, Mark Ross, Brain, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374736/ https://www.ncbi.nlm.nih.gov/pubmed/32418993 http://dx.doi.org/10.1038/s41416-020-0882-y |
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